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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1975 5
1976 2
1977 10
1978 3
1979 7
1980 11
1981 6
1982 15
1983 10
1984 9
1985 16
1986 11
1987 11
1988 13
1989 12
1990 12
1991 19
1992 16
1993 14
1994 33
1995 26
1996 21
1997 22
1998 27
1999 30
2000 46
2001 55
2002 33
2003 42
2004 49
2005 57
2006 77
2007 82
2008 118
2009 91
2010 104
2011 100
2012 108
2013 82
2014 105
2015 78
2016 82
2017 71
2018 73
2019 87
2020 97
2021 97
2022 86
2023 68
2024 21

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2,046 results

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Page 1
Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing.
Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA, Naeger DM, Bandyopadhyay S, Shah K, Cech L, Thomas NJ, Gupta A, Gonzalez M, Do H, Tan L, Bacaltos B, Gomez-Sjoberg R, Gubens M, Jahan T, Kratz JR, Jablons D, Neff N, Doebele RC, Weissman J, Blakely CM, Darmanis S, Bivona TG. Maynard A, et al. Among authors: schenk el. Cell. 2020 Sep 3;182(5):1232-1251.e22. doi: 10.1016/j.cell.2020.07.017. Epub 2020 Aug 20. Cell. 2020. PMID: 32822576 Free PMC article.
Cancer cells surviving therapy as residual disease (RD) expressed an alveolar-regenerative cell signature suggesting a therapy-induced primitive cell-state transition, whereas those present at on-therapy progressive disease (PD) upregulated kynurenine, plasminogen, and gap-juncti …
Cancer cells surviving therapy as residual disease (RD) expressed an alveolar-regenerative cell signature suggesting a therapy-induced primi …
Magnesium sensing via LFA-1 regulates CD8(+) T cell effector function.
Lötscher J, Martí I Líndez AA, Kirchhammer N, Cribioli E, Giordano Attianese GMP, Trefny MP, Lenz M, Rothschild SI, Strati P, Künzli M, Lotter C, Schenk SH, Dehio P, Löliger J, Litzler L, Schreiner D, Koch V, Page N, Lee D, Grählert J, Kuzmin D, Burgener AV, Merkler D, Pless M, Balmer ML, Reith W, Huwyler J, Irving M, King CG, Zippelius A, Hess C. Lötscher J, et al. Among authors: schenk sh. Cell. 2022 Feb 17;185(4):585-602.e29. doi: 10.1016/j.cell.2021.12.039. Epub 2022 Jan 19. Cell. 2022. PMID: 35051368 Free article.
Here, we show that the co-stimulatory cell-surface molecule LFA-1 requires magnesium to adopt its active conformation on CD8(+) T cells, thereby augmenting calcium flux, signal transduction, metabolic reprogramming, immune synapse formation, and, as a consequence, specific …
Here, we show that the co-stimulatory cell-surface molecule LFA-1 requires magnesium to adopt its active conformation on CD8(+) T cel …
Tumor-Infiltrating Lymphocytes and Their Prognostic Value in Cutaneous Melanoma.
Maibach F, Sadozai H, Seyed Jafari SM, Hunger RE, Schenk M. Maibach F, et al. Among authors: schenk m. Front Immunol. 2020 Sep 10;11:2105. doi: 10.3389/fimmu.2020.02105. eCollection 2020. Front Immunol. 2020. PMID: 33013886 Free PMC article. Review.
Nevertheless, TIL enumeration in the current literature primarily relies upon single marker immunohistochemistry analyses of major lymphocyte subsets such as conventional T cells (CD3, CD4, CD8), regulatory T cells (FOXP3) and B cells (CD20). ...
Nevertheless, TIL enumeration in the current literature primarily relies upon single marker immunohistochemistry analyses of major lymphocyt …
Definition: Pseudoneglect.
Ludwig K, Schenk T. Ludwig K, et al. Among authors: schenk t. Cortex. 2022 Oct;155:390-391. doi: 10.1016/j.cortex.2022.07.007. Epub 2022 Aug 6. Cortex. 2022. PMID: 36038377 No abstract available.
Eight-week, multimodal exercise counteracts a progress of chemotherapy-induced peripheral neuropathy and improves balance and strength in metastasized colorectal cancer patients: a randomized controlled trial.
Zimmer P, Trebing S, Timmers-Trebing U, Schenk A, Paust R, Bloch W, Rudolph R, Streckmann F, Baumann FT. Zimmer P, et al. Among authors: schenk a. Support Care Cancer. 2018 Feb;26(2):615-624. doi: 10.1007/s00520-017-3875-5. Epub 2017 Sep 30. Support Care Cancer. 2018. PMID: 28963591 Clinical Trial.
Moreover, endurance capacity (6MWT), strength (h1RM) and balance (GGT-Reha) were evaluated before (t (0)) and after (t (1)) the intervention as well as after 4 weeks follow-up (t(2)). RESULTS: Neuropathic symptoms remained stable in the IG over time, while CI …
Moreover, endurance capacity (6MWT), strength (h1RM) and balance (GGT-Reha) were evaluated before (t (0)) and after (t (1)) th …
Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results.
Palmer CD, Rappaport AR, Davis MJ, Hart MG, Scallan CD, Hong SJ, Gitlin L, Kraemer LD, Kounlavouth S, Yang A, Smith L, Schenk D, Skoberne M, Taquechel K, Marrali M, Jaroslavsky JR, Nganje CN, Maloney E, Zhou R, Navarro-Gomez D, Greene AC, Grotenbreg G, Greer R, Blair W, Cao MD, Chan S, Bae K, Spira AI, Roychowdhury S, Carbone DP, Henick BS, Drake CG, Solomon BJ, Ahn DH, Mahipal A, Maron SB, Johnson B, Rousseau R, Yelensky R, Liao CY, Catenacci DVT, Allen A, Ferguson AR, Jooss K. Palmer CD, et al. Among authors: schenk d. Nat Med. 2022 Aug;28(8):1619-1629. doi: 10.1038/s41591-022-01937-6. Epub 2022 Aug 15. Nat Med. 2022. PMID: 35970920 Clinical Trial.
Checkpoint inhibitor (CPI) therapies provide limited benefit to patients with tumors of low immune reactivity. T cell-inducing vaccines hold promise to exert long-lasting disease control in combination with CPI therapy. ...Vaccine manufacturing was feasible, with vaccinati …
Checkpoint inhibitor (CPI) therapies provide limited benefit to patients with tumors of low immune reactivity. T cell-inducing vaccin …
Dunes on Pluto.
Telfer MW, Parteli EJR, Radebaugh J, Beyer RA, Bertrand T, Forget F, Nimmo F, Grundy WM, Moore JM, Stern SA, Spencer J, Lauer TR, Earle AM, Binzel RP, Weaver HA, Olkin CB, Young LA, Ennico K, Runyon K; New Horizons Geology, Geophysics and Imaging Science Theme Team; Buie M, Buratti B, Cheng A, Kavelaars JJ, Linscott I, McKinnon WB, Reitsema H, Reuter D, Schenk P, Showalter M, Tyler L. Telfer MW, et al. Among authors: schenk p. Science. 2018 Jun 1;360(6392):992-997. doi: 10.1126/science.aao2975. Science. 2018. PMID: 29853681
Springs ecosystem classification.
Stevens LE, Schenk ER, Springer AE. Stevens LE, et al. Among authors: schenk er. Ecol Appl. 2021 Jan;31(1):e2218. doi: 10.1002/eap.2218. Epub 2020 Oct 12. Ecol Appl. 2021. PMID: 32799393 Review.
Antigen recognition detains CD8(+) T cells at the blood-brain barrier and contributes to its breakdown.
Aydin S, Pareja J, Schallenberg VM, Klopstein A, Gruber T, Page N, Bouillet E, Blanchard N, Liblau R, Körbelin J, Schwaninger M, Johnson AJ, Schenk M, Deutsch U, Merkler D, Engelhardt B. Aydin S, et al. Among authors: schenk m. Nat Commun. 2023 May 30;14(1):3106. doi: 10.1038/s41467-023-38703-2. Nat Commun. 2023. PMID: 37253744 Free PMC article.
Blood-brain barrier (BBB) breakdown and immune cell infiltration into the central nervous system (CNS) are early hallmarks of multiple sclerosis (MS). High numbers of CD8(+) T cells are found in MS lesions, and antigen (Ag) presentation at the BBB has been proposed to prom …
Blood-brain barrier (BBB) breakdown and immune cell infiltration into the central nervous system (CNS) are early hallmarks of multiple scler …
Evolution-inspired engineering of nonribosomal peptide synthetases.
Bozhüyük KAJ, Präve L, Kegler C, Schenk L, Kaiser S, Schelhas C, Shi YN, Kuttenlochner W, Schreiber M, Kandler J, Alanjary M, Mohiuddin TM, Groll M, Hochberg GKA, Bode HB. Bozhüyük KAJ, et al. Among authors: schenk l. Science. 2024 Mar 22;383(6689):eadg4320. doi: 10.1126/science.adg4320. Epub 2024 Mar 22. Science. 2024. PMID: 38513038
In this work, we describe a detailed phylogenetic analysis of several bacterial NRPSs that led to the identification of yet undescribed recombination sites within the thiolation (T) domain that can be used for NRPS engineering. We then developed an evolution-inspired "eXch …
In this work, we describe a detailed phylogenetic analysis of several bacterial NRPSs that led to the identification of yet undescribed reco …
2,046 results