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Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct.
Gehrlein A, Udayar V, Anastasi N, Morella ML, Ruf I, Brugger D, von der Mark S, Thoma R, Rufer A, Heer D, Pfahler N, Jochner A, Niewoehner J, Wolf L, Fueth M, Ebeling M, Villaseñor R, Zhu Y, Deen MC, Shan X, Ehsaei Z, Taylor V, Sidransky E, Vocadlo DJ, Freskgård PO, Jagasia R. Gehrlein A, et al. Among authors: udayar v. Nat Commun. 2023 Apr 12;14(1):2057. doi: 10.1038/s41467-023-37632-4. Nat Commun. 2023. PMID: 37045813 Free PMC article.
Lipid-anchored drugs for delivery into subcellular compartments.
Rajendran L, Udayar V, Goodger ZV. Rajendran L, et al. Among authors: udayar v. Trends Pharmacol Sci. 2012 Apr;33(4):215-22. doi: 10.1016/j.tips.2012.01.006. Epub 2012 Mar 3. Trends Pharmacol Sci. 2012. PMID: 22385603 Review.
Superresolution imaging of amyloid fibrils with binding-activated probes.
Ries J, Udayar V, Soragni A, Hornemann S, Nilsson KP, Riek R, Hock C, Ewers H, Aguzzi AA, Rajendran L. Ries J, et al. Among authors: udayar v. ACS Chem Neurosci. 2013 Jul 17;4(7):1057-61. doi: 10.1021/cn400091m. Epub 2013 Apr 22. ACS Chem Neurosci. 2013. PMID: 23594172 Free PMC article.
A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aβ production.
Buggia-Prévot V, Fernandez CG, Udayar V, Vetrivel KS, Elie A, Roseman J, Sasse VA, Lefkow M, Meckler X, Bhattacharyya S, George M, Kar S, Bindokas VP, Parent AT, Rajendran L, Band H, Vassar R, Thinakaran G. Buggia-Prévot V, et al. Among authors: udayar v. Cell Rep. 2013 Dec 26;5(6):1552-63. doi: 10.1016/j.celrep.2013.12.006. Cell Rep. 2013. PMID: 24373286 Free PMC article.