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Page 1
Exposure to microbial products followed by loss of Tet2 promotes myelodysplastic syndrome via remodeling HSCs.
J Exp Med. 2023 Jul 3;220(7):e20220962. doi: 10.1084/jem.20220962. Epub 2023 Apr 18.
J Exp Med. 2023.
PMID: 37071125
Free PMC article.
Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome.
Yokomizo-Nakano T, Kubota S, Bai J, Hamashima A, Morii M, Sun Y, Katagiri S, Iimori M, Kanai A, Tanaka D, Oshima M, Harada Y, Ohyashiki K, Iwama A, Harada H, Osato M, Sashida G.
Yokomizo-Nakano T, et al. Among authors: hamashima a.
Cancer Res. 2020 Jun 15;80(12):2523-2536. doi: 10.1158/0008-5472.CAN-19-3167. Epub 2020 Apr 27.
Cancer Res. 2020.
PMID: 32341038
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TIF1β activates leukemic transcriptional program in HSCs and promotes BCR::ABL1-induced myeloid leukemia.
Morii M, Kubota S, Iimori M, Yokomizo-Nakano T, Hamashima A, Bai J, Nishimura A, Tasaki M, Ando Y, Araki K, Sashida G.
Morii M, et al. Among authors: hamashima a.
Leukemia. 2024 Jun;38(6):1275-1286. doi: 10.1038/s41375-024-02276-w. Epub 2024 May 11.
Leukemia. 2024.
PMID: 38734786
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Chromatin modifier Hmga2 promotes adult hematopoietic stem cell function and blood regeneration in stress conditions.
Kubota S, Sun Y, Morii M, Bai J, Ideue T, Hirayama M, Sorin S, Eerdunduleng, Yokomizo-Nakano T, Osato M, Hamashima A, Iimori M, Araki K, Umemoto T, Sashida G.
Kubota S, et al. Among authors: hamashima a.
EMBO J. 2024 May 29. doi: 10.1038/s44318-024-00122-4. Online ahead of print.
EMBO J. 2024.
PMID: 38811851
Free article.
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The acidic domain of Hmga2 and the domain's linker region are critical for driving self-renewal of hematopoietic stem cell.
Sun Y, Kubota S, Iimori M, Hamashima A, Murakami H, Bai J, Morii M, Yokomizo-Nakano T, Osato M, Araki K, Sashida G.
Sun Y, et al. Among authors: hamashima a.
Int J Hematol. 2022 Apr;115(4):553-562. doi: 10.1007/s12185-021-03274-9. Epub 2022 Jan 24.
Int J Hematol. 2022.
PMID: 35067851
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