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Page 1
Lipid Nanoparticle Encapsulation Empowers Poly(I:C) to Activate Cytoplasmic RLRs and Thereby Increases Its Adjuvanticity.
Small. 2024 Mar;20(10):e2306892. doi: 10.1002/smll.202306892. Epub 2023 Oct 22.
Small. 2024.
PMID: 37867244
Delivery routes matter: Safety and efficacy of intratumoral immunotherapy.
De Lombaerde E, De Wever O, De Geest BG.
De Lombaerde E, et al.
Biochim Biophys Acta Rev Cancer. 2021 Apr;1875(2):188526. doi: 10.1016/j.bbcan.2021.188526. Epub 2021 Feb 20.
Biochim Biophys Acta Rev Cancer. 2021.
PMID: 33617921
Review.
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Lipid Nanoparticle Delivery Alters the Adjuvanticity of the TLR9 Agonist CpG by Innate Immune Activation in Lymphoid Tissue.
Zhong Z, Chen Y, Deswarte K, Lauwers H, De Lombaerde E, Cui X, Van Herck S, Ye T, Gontsarik M, Lienenklaus S, Sanders NN, Lambrecht BN, De Koker S, De Geest BG.
Zhong Z, et al. Among authors: de lombaerde e.
Adv Healthc Mater. 2023 Dec;12(32):e2301687. doi: 10.1002/adhm.202301687. Epub 2023 Oct 11.
Adv Healthc Mater. 2023.
PMID: 37772637
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Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids.
Lamoot A, Lammens J, De Lombaerde E, Zhong Z, Gontsarik M, Chen Y, De Beer TRM, De Geest BG.
Lamoot A, et al. Among authors: de lombaerde e.
Biomater Sci. 2023 Jun 13;11(12):4327-4334. doi: 10.1039/d2bm02031a.
Biomater Sci. 2023.
PMID: 37073472
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