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Menin inhibitor ziftomenib (KO-539) synergizes with drugs targeting chromatin regulation or apoptosis and sensitizes acute myeloid leukemia with MLL rearrangement or NPM1 mutation to venetoclax.
Rausch J, Dzama MM, Dolgikh N, Stiller HL, Bohl SR, Lahrmann C, Kunz K, Kessler L, Echchannaoui H, Chen CW, Kindler T, Döhner K, Burrows F, Theobald M, Sasca D, Kühn MWM. Rausch J, et al. Among authors: dzama mm. Haematologica. 2023 Oct 1;108(10):2837-2843. doi: 10.3324/haematol.2022.282160. Haematologica. 2023. PMID: 37102614 Free PMC article. No abstract available.
A bacterial homolog YciH of eukaryotic translation initiation factor eIF1 regulates stress-related gene expression and is unlikely to be involved in translation initiation fidelity.
Osterman IA, Evfratov SA, Dzama MM, Pletnev PI, Kovalchuk SI, Butenko IO, Pobeguts OV, Golovina AY, Govorun VM, Bogdanov AA, Sergiev PV, Dontsova OA. Osterman IA, et al. Among authors: dzama mm. RNA Biol. 2015;12(9):966-71. doi: 10.1080/15476286.2015.1069464. RNA Biol. 2015. PMID: 26177339 Free PMC article.