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Knockdown of the Shwachman-Diamond syndrome gene, SBDS, induces galectin-1 expression and impairs cell growth.
Yamaguchi M, Sera Y, Toga-Yamaguchi H, Kanegane H, Iguchi Y, Fujimura K. Yamaguchi M, et al. Among authors: sera y. Int J Hematol. 2024 Apr;119(4):383-391. doi: 10.1007/s12185-024-03709-z. Epub 2024 Jan 19. Int J Hematol. 2024. PMID: 38240987
After 3 days of culture, the growth of LCL-SDS cell lines was considerably less than that of control donor cells. By annealing control primer-based GeneFishing PCR screening, we found that galectin-1 (Gal-1) mRNA expression was elevated in LCL-SDS cells. ...
After 3 days of culture, the growth of LCL-SDS cell lines was considerably less than that of control donor cells. By annealing contro …
Evaluation of reference ranges for fatty acids in serum.
Sera RK, McBride JH, Higgins SA, Rodgerson DO. Sera RK, et al. J Clin Lab Anal. 1994;8(2):81-5. doi: 10.1002/jcla.1860080205. J Clin Lab Anal. 1994. PMID: 8189326
However, due to the non-Gaussian distributions of some serum fatty acids, it is necessary to calculate reference ranges non-parametrically. Serum from blood donors (n = 130) were collected and analyzed for total fatty acids by gas-liquid chromatography. ...
However, due to the non-Gaussian distributions of some serum fatty acids, it is necessary to calculate reference ranges non-parametrically. …
Adding In Silico Assessment of Potential Splice Aberration to the Integrated Evaluation of BRCA Gene Unclassified Variants.
Vallée MP, Di Sera TL, Nix DA, Paquette AM, Parsons MT, Bell R, Hoffman A, Hogervorst FB, Goldgar DE, Spurdle AB, Tavtigian SV. Vallée MP, et al. Among authors: di sera tl. Hum Mutat. 2016 Jul;37(7):627-39. doi: 10.1002/humu.22973. Epub 2016 Apr 15. Hum Mutat. 2016. PMID: 26913838 Free PMC article.
Here, we calibrated output from the splice-site fitness program MaxEntScan to generate spliceogenicity-based prior probabilities of pathogenicity for BRCA gene variants; these range from 0.97 for variants with high probability to damage a donor or acceptor to 0.02 for exon …
Here, we calibrated output from the splice-site fitness program MaxEntScan to generate spliceogenicity-based prior probabilities of pathogen …
Site-Specific Integration by Recruitment of a Complex of phiC31 Integrase and Donor DNA to a Target Site by Using a Tandem, Artificial Zinc-Finger Protein.
Sumikawa T, Ohno S, Watanabe T, Yamamoto R, Yamano M, Mori T, Mori K, Tobimatsu T, Sera T. Sumikawa T, et al. Among authors: sera t. Biochemistry. 2018 Dec 18;57(50):6868-6877. doi: 10.1021/acs.biochem.8b00979. Epub 2018 Dec 6. Biochemistry. 2018. PMID: 30462489
A Tandem AZP in which two AZPs recognize specific 19 bp targets in a donor and acceptor DNA was expected to site-specifically recruit the donor DNA to the acceptor DNA. Thereafter, an exogenously added integrase was expected to integrate the donor DNA into a …
A Tandem AZP in which two AZPs recognize specific 19 bp targets in a donor and acceptor DNA was expected to site-specifically recruit …
Hematopoietic stem cell origin of human fibroblasts: cell culture studies of female recipients of gender-mismatched stem cell transplantation and patients with chronic myelogenous leukemia.
Shirai K, Sera Y, Bulkeley W, Mehrotra M, Moussa O, LaRue AC, Watson DK, Stuart RK, Lazarchick J, Ogawa M. Shirai K, et al. Among authors: sera y. Exp Hematol. 2009 Dec;37(12):1464-71. doi: 10.1016/j.exphem.2009.09.008. Epub 2009 Sep 26. Exp Hematol. 2009. PMID: 19786066 Free PMC article.
RESULTS: All cultured fibroblasts from female recipients of male cells showed the presence of Y chromosome, indicating the donor origin of fibroblasts. Cultured fibroblasts from the CML patients revealed the presence of BCR-ABL translocation. ...
RESULTS: All cultured fibroblasts from female recipients of male cells showed the presence of Y chromosome, indicating the donor orig …
Differential splenic migration of dendritic cells after immunologic unresponsiveness in rat hepatic allografts induced by pretransplant donor-specific transfusion.
Ohshiro H, Yamaguchi Y, Okabe K, Takai E, Goto M, Zhang JL, Uchino S, Yamada S, Ishihara K, Furuhashi T, Mori K, Ikeda S, Sera Y, Ogawa M. Ohshiro H, et al. Among authors: sera y. J Surg Res. 2001 Nov;101(1):29-36. doi: 10.1006/jsre.2001.6228. J Surg Res. 2001. PMID: 11676551
BACKGROUND: Donor dendritic cells migrate into the recipient spleen after hepatic transplantation. ...METHODS: Donor dendritic cells were identified with anti-rat dendritic cell (OX-62) and anti-donor class II MHC (RT1B(a)) (OX-76) antibodies. ...
BACKGROUND: Donor dendritic cells migrate into the recipient spleen after hepatic transplantation. ...METHODS: Donor dendritic …
Novel compound heterozygous mutations for lipoprotein lipase deficiency. A G-to-T transversion at the first position of exon 5 causing G154V missense mutation and a 5' splice site mutation of intron 8.
Ikeda Y, Takagi A, Nakata Y, Sera Y, Hyoudou S, Hamamoto K, Nishi Y, Yamamoto A. Ikeda Y, et al. Among authors: sera y. J Lipid Res. 2001 Jul;42(7):1072-81. J Lipid Res. 2001. PMID: 11441134 Free article. Clinical Trial.
The patient was a compound heterozygote for novel mutations consisting of a G-to-T transversion at the first nucleotide of exon 5 [+1 position of 3' acceptor splice site (3'-ass) of intron 4] and a T-to-C transition in the invariant GT at position +2 of the 5' donor splice …
The patient was a compound heterozygote for novel mutations consisting of a G-to-T transversion at the first nucleotide of exon 5 [+1 positi …
A family-based study of hyperinsulinemia and hypertriglyceridemia in heterozygous lipoprotein lipase deficiency.
Ikeda Y, Takagi A, Nakata Y, Sera Y, Hyoudou S, Hamamoto K, Nishi Y, Yamamoto A. Ikeda Y, et al. Among authors: sera y. Clin Chim Acta. 2002 Feb;316(1-2):179-85. doi: 10.1016/s0009-8981(01)00746-x. Clin Chim Acta. 2002. PMID: 11750290
CASE REPORT: A case is presented of predisposing a patient's father with obligate heterozygous lipoprotein lipase (LPL) deficiency to mild hypertriglyceridemia in Japanese I-family members (n=8) with patient DI, who was a compound heterozygote for a novel missense mutation of G15 …
CASE REPORT: A case is presented of predisposing a patient's father with obligate heterozygous lipoprotein lipase (LPL) deficiency to mild h …