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3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration.
Clin Transl Sci. 2021 Sep;14(5):1659-1680. doi: 10.1111/cts.13066. Epub 2021 Jun 16.
Clin Transl Sci. 2021.
PMID: 33982436
Free PMC article.
Review.
CD28 regulates the translation of Bcl-xL via the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway.
Wu LX, La Rose J, Chen L, Neale C, Mak T, Okkenhaug K, Wange R, Rottapel R.
Wu LX, et al. Among authors: wange r.
J Immunol. 2005 Jan 1;174(1):180-94. doi: 10.4049/jimmunol.174.1.180.
J Immunol. 2005.
PMID: 15611240
In concert with the TCR, CD28 promotes T cell survival by regulating the expression of the antiapoptotic protein Bcl-x(L). The mechanism by which CD28 mediates the induction of Bcl-x(L) remains unknown. We show that although signaling through the TCR is sufficient t …
In concert with the TCR, CD28 promotes T cell survival by regulating the expression of the antiapoptotic protein Bcl-x(L). The mechan …
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Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists.
Madrenas J, Wange RL, Wang JL, Isakov N, Samelson LE, Germain RN.
Madrenas J, et al. Among authors: wange rl.
Science. 1995 Jan 27;267(5197):515-8. doi: 10.1126/science.7824949.
Science. 1995.
PMID: 7824949
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Effects of oat bran, processed to different molecular weights of beta-glucan, on plasma lipids and caecal formation of SCFA in mice.
Immerstrand T, Andersson KE, Wange C, Rascon A, Hellstrand P, Nyman M, Cui SW, Bergenståhl B, Trägårdh C, Oste R.
Immerstrand T, et al. Among authors: wange c.
Br J Nutr. 2010 Aug;104(3):364-73. doi: 10.1017/S0007114510000553. Epub 2010 Mar 25.
Br J Nutr. 2010.
PMID: 20334710
Moreover, the difference in viscous properties between the processed OB (from 0.11 to 17.7 l/g) did not appear to play a major role in the cholesterol-lowering properties. ...
Moreover, the difference in viscous properties between the processed OB (from 0.11 to 17.7 l/g) did not appear to play a major role i …
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