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Stereoretentive enantioconvergent reactions.
Bennett SH, Bestwick JS, Demertzidou VP, Jones DJ, Jones HE, Richard F, Homer JA, Street-Jeakings R, Tiberia AF, Lawrence AL. Bennett SH, et al. Among authors: homer ja. Nat Chem. 2024 Apr 17. doi: 10.1038/s41557-024-01504-1. Online ahead of print. Nat Chem. 2024. PMID: 38632365
Mushroom-Derived Indole Alkaloids.
Homer JA, Sperry J. Homer JA, et al. J Nat Prod. 2017 Jul 28;80(7):2178-2187. doi: 10.1021/acs.jnatprod.7b00390. Epub 2017 Jul 19. J Nat Prod. 2017. PMID: 28722414 Review.
Accelerated SuFEx Click Chemistry For Modular Synthesis.
Smedley CJ, Homer JA, Gialelis TL, Barrow AS, Koelln RA, Moses JE. Smedley CJ, et al. Among authors: homer ja. Angew Chem Int Ed Engl. 2022 Jan 21;61(4):e202112375. doi: 10.1002/anie.202112375. Epub 2021 Dec 7. Angew Chem Int Ed Engl. 2022. PMID: 34755436 Free PMC article.
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors.
Cheng Y, Li G, Smedley CJ, Giel MC, Kitamura S, Woehl JL, Bianco G, Forli S, Homer JA, Cappiello JR, Wolan DW, Moses JE, Sharpless KB. Cheng Y, et al. Among authors: homer ja. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2208540119. doi: 10.1073/pnas.2208540119. Epub 2022 Sep 7. Proc Natl Acad Sci U S A. 2022. PMID: 36070343 Free PMC article.
Shapeshifting bullvalene-linked vancomycin dimers as effective antibiotics against multidrug-resistant gram-positive bacteria.
Ottonello A, Wyllie JA, Yahiaoui O, Sun S, Koelln RA, Homer JA, Johnson RM, Murray E, Williams P, Bolla JR, Robinson CV, Fallon T, Soares da Costa TP, Moses JE. Ottonello A, et al. Among authors: homer ja. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2208737120. doi: 10.1073/pnas.2208737120. Epub 2023 Apr 3. Proc Natl Acad Sci U S A. 2023. PMID: 37011186 Free PMC article.
Modular synthesis of functional libraries by accelerated SuFEx click chemistry.
Homer JA, Koelln RA, Barrow AS, Gialelis TL, Boiarska Z, Steinohrt NS, Lee EF, Yang WH, Johnson RM, Chung T, Habowski AN, Vishwakarma DS, Bhunia D, Avanzi C, Moorhouse AD, Jackson M, Tuveson DA, Lyons SK, Lukey MJ, Fairlie WD, Haider SM, Steinmetz MO, Prota AE, Moses JE. Homer JA, et al. Chem Sci. 2024 Mar 4;15(11):3879-3892. doi: 10.1039/d3sc05729a. eCollection 2024 Mar 13. Chem Sci. 2024. PMID: 38487227 Free PMC article.