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Partial Characterization and Immunomodulatory Effects of Exopolysaccharides from Streptococcus thermophilus SBC8781 during Soy Milk and Cow Milk Fermentation.
Nakata H, Imamura Y, Saha S, Lobo RE, Kitahara S, Araki S, Tomokiyo M, Namai F, Hiramitsu M, Inoue T, Nishiyama K, Villena J, Kitazawa H. Nakata H, et al. Among authors: tomokiyo m. Foods. 2023 Jun 15;12(12):2374. doi: 10.3390/foods12122374. Foods. 2023. PMID: 37372583 Free PMC article.
In this work, EPSs from S. thermophilus SBC8781 were isolated after soy milk (EPS-s) or cow milk (EPS-m) fermentation, identified, and characterized in their abilities to modulate immunity in porcine intestinal epithelial cells. ...For immunomodulatory assays, intestinal e …
In this work, EPSs from S. thermophilus SBC8781 were isolated after soy milk (EPS-s) or cow milk (EPS-m) fermentation, identified, an …
Effect of Simulated Dental Pulpal Pressure Using Fetal Bovine Serum for the Bonding Performance of Contemporary Adhesive to Dentin.
Li Y, Maeno M, Cifuentes-Jimenez CC, Komoto M, Liu Y, Nara Y, Sano H, Alvarez-Lloret P, Yamauti M, Tomokiyo A. Li Y, et al. Among authors: tomokiyo a. Polymers (Basel). 2024 Apr 26;16(9):1219. doi: 10.3390/polym16091219. Polymers (Basel). 2024. PMID: 38732688 Free PMC article.
Resin composite build-ups were prepared, and teeth were stored in water (37 C) for 24 h (24 h) and 3 months (3 m). Then, teeth were sectioned to obtain resin-dentin bonded beams and tested to determine the TBS. ...Storage after 3 m also decreased TBS despite the SPP …
Resin composite build-ups were prepared, and teeth were stored in water (37 C) for 24 h (24 h) and 3 months (3 m). Then, teeth were s …
Evaluation of Porcine Intestinal Epitheliocytes as an In vitro Immunoassay System for the Selection of Probiotic Bifidobacteria to Alleviate Inflammatory Bowel Disease.
Sato N, Yuzawa M, Aminul MI, Tomokiyo M, Albarracin L, Garcia-Castillo V, Ideka-Ohtsubo W, Iwabuchi N, Xiao JZ, Garcia-Cancino A, Villena J, Kitazawa H. Sato N, et al. Among authors: tomokiyo m. Probiotics Antimicrob Proteins. 2021 Jun;13(3):824-836. doi: 10.1007/s12602-020-09694-z. Probiotics Antimicrob Proteins. 2021. PMID: 32779098
Our results demonstrated that DSS administration can alter the epithelial barrier created in vitro by PIE cells and induce a potent inflammatory response, characterized by increases in the expression levels of several inflammatory factors including TNF-alpha, IL-1alpha, CCL4, CCL …
Our results demonstrated that DSS administration can alter the epithelial barrier created in vitro by PIE cells and induce a potent inflamma …
Effects of plantar flexion resistive moment generated by an ankle-foot orthosis with an oil damper on the gait of stroke patients: a pilot study.
Yamamoto S, Tomokiyo N, Yasui T, Kawaguchi T. Yamamoto S, et al. Among authors: tomokiyo n. Prosthet Orthot Int. 2013 Jun;37(3):212-21. doi: 10.1177/0309364612460266. Epub 2012 Oct 17. Prosthet Orthot Int. 2013. PMID: 23075466
RESULTS: The resistive moment was observed in the former half in stance of the paretic limb, and its magnitude was less than 10 N m. Some gait parameters related to terminal stance and preswing were affected by the amount of resistive moment. ...
RESULTS: The resistive moment was observed in the former half in stance of the paretic limb, and its magnitude was less than 10 N m. …
The 99 and 170 loop-modified factor VIIa mutants show enhanced catalytic activity without tissue factor.
Soejima K, Yuguchi M, Mizuguchi J, Tomokiyo K, Nakashima T, Nakagaki T, Iwanaga S. Soejima K, et al. Among authors: tomokiyo k. J Biol Chem. 2002 Dec 13;277(50):49027-35. doi: 10.1074/jbc.M203091200. Epub 2002 Oct 2. J Biol Chem. 2002. PMID: 12364340 Free article.
This enhancement was due to a decrease in the K(m) value but not to an increase in the k(cat) value. On the other hand, the k(cat)/K(m) value for S-2288 hydrolysis by VIIa-39 (17.9 mm(-)1 s(-)1) was 18-fold higher than that of wild-type (1.0 mm(-)1 s(-)1) in the abs …
This enhancement was due to a decrease in the K(m) value but not to an increase in the k(cat) value. On the other hand, the k(cat)/K( …
Exposure to transforming growth factor-β1 after basic fibroblast growth factor promotes the fibroblastic differentiation of human periodontal ligament stem/progenitor cell lines.
Kono K, Maeda H, Fujii S, Tomokiyo A, Yamamoto N, Wada N, Monnouchi S, Teramatsu Y, Hamano S, Koori K, Akamine A. Kono K, et al. Among authors: tomokiyo a. Cell Tissue Res. 2013 May;352(2):249-63. doi: 10.1007/s00441-012-1543-0. Epub 2013 Jan 17. Cell Tissue Res. 2013. PMID: 23324989
Furthermore, bFGF stimulated cell proliferation of these cell lines and significantly increased the number of cells in phase G2/M in the cell lines. Exposure to TGFbeta1 for 2 days induced gene expression of ACTA2 and COL1 in both cell lines and FBN1 in cell line 1-11 alon …
Furthermore, bFGF stimulated cell proliferation of these cell lines and significantly increased the number of cells in phase G2/M in …