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Page 1
In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer.
Cell. 2021 Mar 4;184(5):1262-1280.e22. doi: 10.1016/j.cell.2021.02.019. Epub 2021 Feb 25.
Cell. 2021.
PMID: 33636129
Free PMC article.
In vitro modeling of CD8+ T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40.
Wu JE, Manne S, Ngiow SF, Baxter AE, Huang H, Freilich E, Clark ML, Lee JH, Chen Z, Khan O, Staupe RP, Huang YJ, Shi J, Giles JR, Wherry EJ.
Wu JE, et al. Among authors: freilich e.
Sci Immunol. 2023 Aug 25;8(86):eade3369. doi: 10.1126/sciimmunol.ade3369. Epub 2023 Aug 18.
Sci Immunol. 2023.
PMID: 37595022
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The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells.
Baxter AE, Huang H, Giles JR, Chen Z, Wu JE, Drury S, Dalton K, Park SL, Torres L, Simone BW, Klapholz M, Ngiow SF, Freilich E, Manne S, Alcalde V, Ekshyyan V, Berger SL, Shi J, Jordan MS, Wherry EJ.
Baxter AE, et al. Among authors: freilich e.
Immunity. 2023 Jun 13;56(6):1320-1340.e10. doi: 10.1016/j.immuni.2023.05.008.
Immunity. 2023.
PMID: 37315535
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Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers.
Giles JR, Manne S, Freilich E, Oldridge DA, Baxter AE, George S, Chen Z, Huang H, Chilukuri L, Carberry M, Giles L, Weng NP, Young RM, June CH, Schuchter LM, Amaravadi RK, Xu X, Karakousis GC, Mitchell TC, Huang AC, Shi J, Wherry EJ.
Giles JR, et al. Among authors: freilich e.
Immunity. 2022 Mar 8;55(3):557-574.e7. doi: 10.1016/j.immuni.2022.02.004.
Immunity. 2022.
PMID: 35263570
Free PMC article.
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In Vitro Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40.
Wu JE, Manne S, Ngiow SF, Baxter AE, Huang H, Freilich E, Clark ML, Lee JH, Chen Z, Khan O, Staupe RP, Huang YJ, Shi J, Giles JR, Wherry EJ.
Wu JE, et al. Among authors: freilich e.
bioRxiv [Preprint]. 2023 Apr 17:2023.04.17.537229. doi: 10.1101/2023.04.17.537229.
bioRxiv. 2023.
PMID: 37131713
Free PMC article.
Updated.
Preprint.
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High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening.
Gier RA, Budinich KA, Evitt NH, Cao Z, Freilich ES, Chen Q, Qi J, Lan Y, Kohli RM, Shi J.
Gier RA, et al. Among authors: freilich es.
Nat Commun. 2020 Jul 13;11(1):3455. doi: 10.1038/s41467-020-17209-1.
Nat Commun. 2020.
PMID: 32661245
Free PMC article.
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