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Page 1
FGF21 gene therapy as treatment for obesity and insulin resistance.
Jimenez V, Jambrina C, Casana E, Sacristan V, Muñoz S, Darriba S, Rodó J, Mallol C, Garcia M, León X, Marcó S, Ribera A, Elias I, Casellas A, Grass I, Elias G, Ferré T, Motas S, Franckhauser S, Mulero F, Navarro M, Haurigot V, Ruberte J, Bosch F. Jimenez V, et al. Among authors: casana e. EMBO Mol Med. 2018 Aug;10(8):e8791. doi: 10.15252/emmm.201708791. EMBO Mol Med. 2018. PMID: 29987000 Free PMC article.
AAV-mediated BMP7 gene therapy counteracts insulin resistance and obesity.
Casana E, Jimenez V, Jambrina C, Sacristan V, Muñoz S, Rodo J, Grass I, Garcia M, Mallol C, León X, Casellas A, Sánchez V, Franckhauser S, Ferré T, Marcó S, Bosch F. Casana E, et al. Mol Ther Methods Clin Dev. 2022 Mar 16;25:190-204. doi: 10.1016/j.omtm.2022.03.007. eCollection 2022 Jun 9. Mol Ther Methods Clin Dev. 2022. PMID: 35434177 Free PMC article.
Vitamin D Receptor Overexpression in β-Cells Ameliorates Diabetes in Mice.
Morró M, Vilà L, Franckhauser S, Mallol C, Elias G, Ferré T, Molas M, Casana E, Rodó J, Pujol A, Téllez N, Bosch F, Casellas A. Morró M, et al. Among authors: casana e. Diabetes. 2020 May;69(5):927-939. doi: 10.2337/db19-0757. Epub 2020 Feb 21. Diabetes. 2020. PMID: 32086292 Free PMC article.
Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage.
Casellas A, Mallol C, Salavert A, Jimenez V, Garcia M, Agudo J, Obach M, Haurigot V, Vilà L, Molas M, Lage R, Morró M, Casana E, Ruberte J, Bosch F. Casellas A, et al. Among authors: casana e. J Biol Chem. 2015 Jul 3;290(27):16772-85. doi: 10.1074/jbc.M115.642041. Epub 2015 May 13. J Biol Chem. 2015. PMID: 25971976 Free PMC article.