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An evolved AAV variant enables efficient genetic engineering of murine T cells.
Nyberg WA, Ark J, To A, Clouden S, Reeder G, Muldoon JJ, Chung JY, Xie WH, Allain V, Steinhart Z, Chang C, Talbot A, Kim S, Rosales A, Havlik LP, Pimentel H, Asokan A, Eyquem J. Nyberg WA, et al. Among authors: muldoon jj. Cell. 2023 Jan 19;186(2):446-460.e19. doi: 10.1016/j.cell.2022.12.022. Epub 2023 Jan 12. Cell. 2023. PMID: 36638795 Free PMC article.
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes.
Foss DV, Muldoon JJ, Nguyen DN, Carr D, Sahu SU, Hunsinger JM, Wyman SK, Krishnappa N, Mendonsa R, Schanzer EV, Shy BR, Vykunta VS, Allain V, Li Z, Marson A, Eyquem J, Wilson RC. Foss DV, et al. Among authors: muldoon jj. Nat Biomed Eng. 2023 May;7(5):647-660. doi: 10.1038/s41551-023-01032-2. Epub 2023 Apr 25. Nat Biomed Eng. 2023. PMID: 37147433 Free PMC article.
Elucidation and refinement of synthetic receptor mechanisms.
Edelstein HI, Donahue PS, Muldoon JJ, Kang AK, Dolberg TB, Battaglia LM, Allchin ER, Hong M, Leonard JN. Edelstein HI, et al. Among authors: muldoon jj. Synth Biol (Oxf). 2020 Sep 30;5(1):ysaa017. doi: 10.1093/synbio/ysaa017. eCollection 2020. Synth Biol (Oxf). 2020. PMID: 33392392 Free PMC article.
Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection.
Chang CR, Vykunta VS, Goodman DB, Muldoon JJ, Nyberg WA, Liu C, Allain V, Rothrock A, Wang CH, Marson A, Shy BR, Eyquem J. Chang CR, et al. Among authors: muldoon jj. bioRxiv [Preprint]. 2024 Feb 7:2024.02.06.576175. doi: 10.1101/2024.02.06.576175. bioRxiv. 2024. PMID: 38370809 Free PMC article. Preprint.
13 results