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Development and characterization of agonistic antibodies targeting the Ig-like 1 domain of MuSK.
Lim JL, Augustinus R, Plomp JJ, Roya-Kouchaki K, Vergoossen DLE, Fillié-Grijpma Y, Struijk J, Thomas R, Salvatori D, Steyaert C, Blanchetot C, Vanhauwaert R, Silence K, van der Maarel SM, Verschuuren JJ, Huijbers MG. Lim JL, et al. Among authors: augustinus r. Sci Rep. 2023 May 8;13(1):7478. doi: 10.1038/s41598-023-32641-1. Sci Rep. 2023. PMID: 37156800 Free PMC article.
MuSK antibodies, lessons learned from poly- and monoclonality.
Vergoossen DLE, Augustinus R, Huijbers MG. Vergoossen DLE, et al. Among authors: augustinus r. J Autoimmun. 2020 Aug;112:102488. doi: 10.1016/j.jaut.2020.102488. Epub 2020 Jun 4. J Autoimmun. 2020. PMID: 32505442 Free article. Review.
Functional monovalency amplifies the pathogenicity of anti-MuSK IgG4 in myasthenia gravis.
Vergoossen DLE, Plomp JJ, Gstöttner C, Fillié-Grijpma YE, Augustinus R, Verpalen R, Wuhrer M, Parren PWHI, Dominguez-Vega E, van der Maarel SM, Verschuuren JJ, Huijbers MG. Vergoossen DLE, et al. Among authors: augustinus r. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2020635118. doi: 10.1073/pnas.2020635118. Proc Natl Acad Sci U S A. 2021. PMID: 33753489 Free PMC article.