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CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions.
Li E, Benitez C, Boggess SC, Koontz M, Rose IVL, Draeger N, Teter OM, Samelson AJ, Ullian EM, Kampmann M. Li E, et al. Among authors: benitez c. bioRxiv [Preprint]. 2023 Apr 27:2023.04.26.538498. doi: 10.1101/2023.04.26.538498. bioRxiv. 2023. PMID: 37163077 Free PMC article. Preprint.
Tuberous sclerosis complex is associated with a novel human tauopathy.
Hwang JL, Perloff OS, Gaus SE, Benitez C, Alquezar C, Cosme CQ, Nana AL, Vatsavayai SC, Ramos EM, Geschwind DH, Miller BL, Kao AW, Seeley WW. Hwang JL, et al. Among authors: benitez c. Acta Neuropathol. 2023 Jan;145(1):1-12. doi: 10.1007/s00401-022-02521-5. Epub 2022 Dec 5. Acta Neuropathol. 2023. PMID: 36469115 Free PMC article.
Spatial regulation of the actin cytoskeleton by HSF-1 during aging.
Higuchi-Sanabria R, Paul JW 3rd, Durieux J, Benitez C, Frankino PA, Tronnes SU, Garcia G, Daniele JR, Monshietehadi S, Dillin A. Higuchi-Sanabria R, et al. Among authors: benitez c. Mol Biol Cell. 2018 Oct 15;29(21):2522-2527. doi: 10.1091/mbc.E18-06-0362. Epub 2018 Aug 22. Mol Biol Cell. 2018. PMID: 30133343 Free PMC article.
UPRER promotes lipophagy independent of chaperones to extend life span.
Daniele JR, Higuchi-Sanabria R, Durieux J, Monshietehadi S, Ramachandran V, Tronnes SU, Kelet N, Sanchez M, Metcalf MG, Garcia G, Frankino PA, Benitez C, Zeng M, Esping DJ, Joe L, Dillin A. Daniele JR, et al. Among authors: benitez c. Sci Adv. 2020 Jan 1;6(1):eaaz1441. doi: 10.1126/sciadv.aaz1441. eCollection 2020 Jan. Sci Adv. 2020. PMID: 31911951 Free PMC article.
Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and actin stabilization.
Moehle EA, Higuchi-Sanabria R, Tsui CK, Homentcovschi S, Tharp KM, Zhang H, Chi H, Joe L, de Los Rios Rogers M, Sahay A, Kelet N, Benitez C, Bar-Ziv R, Garcia G, Shen K, Frankino PA, Schinzel RT, Shalem O, Dillin A. Moehle EA, et al. Among authors: benitez c. Sci Adv. 2021 Oct 29;7(44):eabj6818. doi: 10.1126/sciadv.abj6818. Epub 2021 Oct 29. Sci Adv. 2021. PMID: 34714674 Free PMC article.