Ythdf is a N6-methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila.
Worpenberg L, Paolantoni C, Longhi S, Mulorz MM, Lence T, Wessels HH, Dassi E, Aiello G, Sutandy FXR, Scheibe M, Edupuganti RR, Busch A, Möckel MM, Vermeulen M, Butter F, König J, Notarangelo M, Ohler U, Dieterich C, Quattrone A, Soldano A, Roignant JY.
Worpenberg L, et al. Among authors: soldano a.
EMBO J. 2021 Feb 15;40(4):e104975. doi: 10.15252/embj.2020104975. Epub 2021 Jan 11.
EMBO J. 2021.
PMID: 33428246
Free PMC article.
N6-methyladenosine (m(6) A) regulates a variety of physiological processes through modulation of RNA metabolism. ...We identify Ythdf as the main m(6) A reader in the nervous system, being required to limit axonal growth. ...
N6-methyladenosine (m(6) A) regulates a variety of physiological processes through modulation of RNA metabolism. ...We identify Ythdf …