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Page 1
Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss.
Zhu X, Fu Z, Chen SY, Ong D, Aceto G, Ho R, Steinberger J, Monast A, Pilon V, Li E, Ta M, Ching K, Adams BN, Negri GL, Choiniere L, Fu L, Pavlakis K, Pirrotte P, Avizonis DZ, Trent J, Weissman BE, Klein Geltink RI, Morin GB, Park M, Huntsman DG, Foulkes WD, Wang Y, Huang S. Zhu X, et al. Among authors: steinberger j. Nat Commun. 2023 May 20;14(1):2894. doi: 10.1038/s41467-023-38594-3. Nat Commun. 2023. PMID: 37210563 Free PMC article.
Cotargeting CDK4/6 and BRD4 Promotes Senescence and Ferroptosis Sensitivity in Cancer.
Zhu X, Fu Z, Dutchak K, Arabzadeh A, Milette S, Steinberger J, Morin G, Monast A, Pilon V, Kong T, Adams BN, Prando Munhoz E, Hosein HJB, Fang T, Su J, Xue Y, Rayes R, Sangwan V, Walsh LA, Chen G, Quail DF, Spicer JD, Park M, Dankort D, Huang S. Zhu X, et al. Among authors: steinberger j. Cancer Res. 2024 Apr 15;84(8):1333-1351. doi: 10.1158/0008-5472.CAN-23-1749. Cancer Res. 2024. PMID: 38277141
Developing anti-neoplastic biotherapeutics against eIF4F.
Steinberger J, Chu J, Maïga RI, Sleiman K, Pelletier J. Steinberger J, et al. Cell Mol Life Sci. 2017 May;74(9):1681-1692. doi: 10.1007/s00018-016-2430-8. Epub 2016 Dec 21. Cell Mol Life Sci. 2017. PMID: 28004147 Free PMC article. Review.
Tracing MYC Expression for Small Molecule Discovery.
Steinberger J, Robert F, Hallé M, Williams DE, Cencic R, Sawhney N, Pelletier D, Williams P, Igarashi Y, Porco JA Jr, Rodriguez AD, Kopp B, Bachmann B, Andersen RJ, Pelletier J. Steinberger J, et al. Cell Chem Biol. 2019 May 16;26(5):699-710.e6. doi: 10.1016/j.chembiol.2019.02.007. Epub 2019 Mar 14. Cell Chem Biol. 2019. PMID: 30880156 Free PMC article.