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2014 1
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Page 1
Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate.
Shiraishi K, Shah PP, Morley MP, Loebel C, Santini GT, Katzen J, Basil MC, Lin SM, Planer JD, Cantu E, Jones DL, Nottingham AN, Li S, Cardenas-Diaz FL, Zhou S, Burdick JA, Jain R, Morrisey EE. Shiraishi K, et al. Among authors: jones dl. Cell. 2023 Mar 30;186(7):1478-1492.e15. doi: 10.1016/j.cell.2023.02.010. Epub 2023 Mar 3. Cell. 2023. PMID: 36870331 Free PMC article.
Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis.
Caporarello N, Lee J, Pham TX, Jones DL, Guan J, Link PA, Meridew JA, Marden G, Yamashita T, Osborne CA, Bhagwate AV, Huang SK, Nicosia RF, Tschumperlin DJ, Trojanowska M, Ligresti G. Caporarello N, et al. Among authors: jones dl. Nat Commun. 2022 Jul 25;13(1):4170. doi: 10.1038/s41467-022-31890-4. Nat Commun. 2022. PMID: 35879310 Free PMC article.
Mechanoepigenetic regulation of extracellular matrix homeostasis via Yap and Taz.
Jones DL, Hallström GF, Jiang X, Locke RC, Evans MK, Bonnevie ED, Srikumar A, Leahy TP, Nijsure MP, Boerckel JD, Mauck RL, Dyment NA. Jones DL, et al. Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2211947120. doi: 10.1073/pnas.2211947120. Epub 2023 May 22. Proc Natl Acad Sci U S A. 2023. PMID: 37216538 Free PMC article.
Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis.
Haak AJ, Kostallari E, Sicard D, Ligresti G, Choi KM, Caporarello N, Jones DL, Tan Q, Meridew J, Diaz Espinosa AM, Aravamudhan A, Maiers JL, Britt RD Jr, Roden AC, Pabelick CM, Prakash YS, Nouraie SM, Li X, Zhang Y, Kass DJ, Lagares D, Tager AM, Varelas X, Shah VH, Tschumperlin DJ. Haak AJ, et al. Among authors: jones dl. Sci Transl Med. 2019 Oct 30;11(516):eaau6296. doi: 10.1126/scitranslmed.aau6296. Sci Transl Med. 2019. PMID: 31666402 Free PMC article.
TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation.
Aravamudhan A, Haak AJ, Choi KM, Meridew JA, Caporarello N, Jones DL, Tan Q, Ligresti G, Tschumperlin DJ. Aravamudhan A, et al. Among authors: jones dl. Am J Physiol Lung Cell Mol Physiol. 2020 May 1;318(5):L852-L863. doi: 10.1152/ajplung.00324.2019. Epub 2020 Mar 11. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32159970 Free PMC article.
ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation.
Jones DL, Meridew JA, Link PA, Ducharme MT, Lydon KL, Choi KM, Caporarello N, Tan Q, Diaz Espinosa AM, Xiong Y, Lee JH, Ye Z, Yan H, Ordog T, Ligresti G, Varelas X, Tschumperlin DJ. Jones DL, et al. J Cell Biol. 2021 May 3;220(5):e202007152. doi: 10.1083/jcb.202007152. J Cell Biol. 2021. PMID: 33625469 Free PMC article.
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