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Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1.
Hall A, Abendroth J, Bolejack MJ, Ceska T, Dell'Aiera S, Ellis V, Fox D 3rd, François C, Muruthi MM, Prével C, Poullennec K, Romanov S, Valade A, Vanbellinghen A, Yano J, Geraerts M. Hall A, et al. Among authors: bolejack mj. ACS Med Chem Lett. 2022 Jun 25;13(7):1099-1108. doi: 10.1021/acsmedchemlett.2c00134. eCollection 2022 Jul 14. ACS Med Chem Lett. 2022. PMID: 35859861 Free PMC article.
Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba.
Tillery L, Barrett K, Goldstein J, Lassner JW, Osterhout B, Tran NL, Xu L, Young RM, Craig J, Chun I, Dranow DM, Abendroth J, Delker SL, Davies DR, Mayclin SJ, Calhoun B, Bolejack MJ, Staker B, Subramanian S, Phan I, Lorimer DD, Myler PJ, Edwards TE, Kyle DE, Rice CA, Morris JC, Leahy JW, Manetsch R, Barrett LK, Smith CL, Van Voorhis WC. Tillery L, et al. Among authors: bolejack mj. PLoS One. 2021 Mar 24;16(3):e0241738. doi: 10.1371/journal.pone.0241738. eCollection 2021. PLoS One. 2021. PMID: 33760815 Free PMC article.
Crystal structure and biophysical characterization of IspD from Burkholderia thailandensis and Mycobacterium paratuberculosis.
Pierce PG, Hartnett BE, Laughlin TM, Blain JM, Mayclin SJ, Bolejack MJ, Myers JB, Higgins TW, Dranow DM, Sullivan A, Lorimer DD, Edwards TE, Hagen TJ, Horn JR, Myler PJ. Pierce PG, et al. Among authors: bolejack mj. Acta Crystallogr F Struct Biol Commun. 2024 Feb 1;80(Pt 2):43-51. doi: 10.1107/S2053230X24000621. Epub 2024 Jan 31. Acta Crystallogr F Struct Biol Commun. 2024. PMID: 38305785