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Quercetin treatment increases H2O2 removal by restoration of endogenous antioxidant activity and blocks isoproterenol-induced cardiac hypertrophy.
de Lacerda Alexandre JV, Viana YIP, David CEB, Cunha PLO, Albuquerque AC, Varela ALN, Kowaltowski AJ, Facundo HT. de Lacerda Alexandre JV, et al. Among authors: varela aln. Naunyn Schmiedebergs Arch Pharmacol. 2021 Feb;394(2):217-226. doi: 10.1007/s00210-020-01953-8. Epub 2020 Sep 15. Naunyn Schmiedebergs Arch Pharmacol. 2021. PMID: 32930861
Pharmacological and molecular docking studies reveal that glibenclamide competitively inhibits diazoxide-induced mitochondrial ATP-sensitive potassium channel activation and pharmacological preconditioning.
Bezerra Palácio P, Brito Lucas AM, Varlla de Lacerda Alexandre J, Oliveira Cunha PL, Ponte Viana YI, Albuquerque AC, Nunes Varela AL, Facundo HT. Bezerra Palácio P, et al. Among authors: nunes varela al. Eur J Pharmacol. 2021 Oct 5;908:174379. doi: 10.1016/j.ejphar.2021.174379. Epub 2021 Jul 26. Eur J Pharmacol. 2021. PMID: 34324857 Free article.