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Year Number of Results
2016 1
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2020 3
2021 2
2022 1
2023 7
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15 results

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Page 1
Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies.
Nicosia L, Spencer GJ, Brooks N, Amaral FMR, Basma NJ, Chadwick JA, Revell B, Wingelhofer B, Maiques-Diaz A, Sinclair O, Camera F, Ciceri F, Wiseman DH, Pegg N, West W, Knurowski T, Frese K, Clegg K, Campbell VL, Cavet J, Copland M, Searle E, Somervaille TCP. Nicosia L, et al. Among authors: amaral fmr. Cancer Cell. 2023 Dec 11;41(12):2136-2153.e13. doi: 10.1016/j.ccell.2023.11.001. Epub 2023 Nov 22. Cancer Cell. 2023. PMID: 37995682 Free article.
A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells.
Ginn L, Maltas J, Baker MJ, Chaturvedi A, Wilson L, Guilbert R, Amaral FMR, Priest L, Mole H, Blackhall F, Diamantopoulou Z, Somervaille TCP, Hurlstone A, Malliri A. Ginn L, et al. Among authors: amaral fmr. Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2300489120. doi: 10.1073/pnas.2300489120. Epub 2023 Sep 25. Proc Natl Acad Sci U S A. 2023. PMID: 37748077 Free PMC article.
HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block.
Maiques-Diaz A, Nicosia L, Basma NJ, Romero-Camarero I, Camera F, Spencer GJ, Amaral FMR, Simeoni F, Wingelhofer B, Williamson AJK, Pierce A, Whetton AD, Somervaille TCP. Maiques-Diaz A, et al. Among authors: amaral fmr. Oncogene. 2022 Oct;41(44):4841-4854. doi: 10.1038/s41388-022-02471-y. Epub 2022 Sep 28. Oncogene. 2022. PMID: 36171271 Free PMC article.
Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.
Simeoni F, Romero-Camarero I, Camera F, Amaral FMR, Sinclair OJ, Papachristou EK, Spencer GJ, Lie-A-Ling M, Lacaud G, Wiseman DH, Carroll JS, Somervaille TCP. Simeoni F, et al. Among authors: amaral fmr. Cell Rep. 2021 Sep 21;36(12):109725. doi: 10.1016/j.celrep.2021.109725. Cell Rep. 2021. PMID: 34551306 Free PMC article.
EVI1 phosphorylation at S436 regulates interactions with CtBP1 and DNMT3A and promotes self-renewal.
Paredes R, Kelly JR, Geary B, Almarzouq B, Schneider M, Pearson S, Narayanan P, Williamson A, Lovell SC, Wiseman DH, Chadwick JA, Jones NJ, Kustikova O, Schambach A, Garner T, Amaral FMR, Pierce A, Stevens A, Somervaille TCP, Whetton AD, Meyer S. Paredes R, et al. Among authors: amaral fmr. Cell Death Dis. 2020 Oct 20;11(10):878. doi: 10.1038/s41419-020-03099-0. Cell Death Dis. 2020. PMID: 33082307 Free PMC article.
15 results