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A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability.
Moretton A, Kourtis S, Gañez Zapater A, Calabrò C, Espinar Calvo ML, Fontaine F, Darai E, Abad Cortel E, Block S, Pascual-Reguant L, Pardo-Lorente N, Ghose R, Vander Heiden MG, Janic A, Müller AC, Loizou JI, Sdelci S. Moretton A, et al. Among authors: darai e. Mol Syst Biol. 2023 Jul 11;19(7):e11267. doi: 10.15252/msb.202211267. Epub 2023 Jun 1. Mol Syst Biol. 2023. PMID: 37259925 Free PMC article.
OPENchip: an on-chip in situ molecular profiling platform for gene expression analysis and oncogenic mutation detection in single circulating tumour cells.
Lee AC, Svedlund J, Darai E, Lee Y, Lee D, Lee HB, Kim SM, Kim O, Bae HJ, Choi A, Lee S, Jeong Y, Song SW, Choi Y, Yeom H, Lee CS, Han W, Lee DS, Jang JY, Madaboosi N, Nilsson M, Kwon S. Lee AC, et al. Among authors: darai e. Lab Chip. 2020 Mar 3;20(5):912-922. doi: 10.1039/c9lc01248f. Lab Chip. 2020. PMID: 32057051
In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and KRAS Point Mutations in Circulating Tumor Cells.
El-Heliebi A, Hille C, Laxman N, Svedlund J, Haudum C, Ercan E, Kroneis T, Chen S, Smolle M, Rossmann C, Krzywkowski T, Ahlford A, Darai E, von Amsberg G, Alsdorf W, König F, Löhr M, de Kruijff I, Riethdorf S, Gorges TM, Pantel K, Bauernhofer T, Nilsson M, Sedlmayr P. El-Heliebi A, et al. Among authors: darai e. Clin Chem. 2018 Mar;64(3):536-546. doi: 10.1373/clinchem.2017.281295. Epub 2018 Jan 4. Clin Chem. 2018. PMID: 29301749