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CDK4/6 inhibition confers protection of normal gut epithelia against gemcitabine and the active metabolite of irinotecan.
Cell Cycle. 2023 Jul;22(13):1563-1582. doi: 10.1080/15384101.2023.2217003. Epub 2023 Jun 2.
Cell Cycle. 2023.
PMID: 37266562
Free PMC article.
Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity.
Isermann T, Şener ÖÇ, Stender A, Klemke L, Winkler N, Neesse A, Li J, Wegwitz F, Moll UM, Schulz-Heddergott R.
Isermann T, et al.
Nat Commun. 2021 Jun 29;12(1):4019. doi: 10.1038/s41467-021-24064-1.
Nat Commun. 2021.
PMID: 34188043
Free PMC article.
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Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition.
Isermann T, Schneider KL, Wegwitz F, De Oliveira T, Conradi LC, Volk V, Feuerhake F, Papke B, Stintzing S, Mundt B, Kühnel F, Moll UM, Schulz-Heddergott R.
Isermann T, et al.
bioRxiv [Preprint]. 2024 Feb 26:2024.02.22.581507. doi: 10.1101/2024.02.22.581507.
bioRxiv. 2024.
PMID: 38464125
Free PMC article.
Preprint.
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