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Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition.
Cazzoli R, Romeo F, Pallavicini I, Peri S, Romanenghi M, Pérez-Valencia JA, Hagag E, Ferrucci F, Elgendy M, Vittorio O, Pece S, Foiani M, Westermarck J, Minucci S. Cazzoli R, et al. Among authors: ferrucci f. Cell Rep. 2023 Jun 27;42(6):112616. doi: 10.1016/j.celrep.2023.112616. Epub 2023 Jun 7. Cell Rep. 2023. PMID: 37289585 Free article.
CRISPR-Cas9-mediated somatic correction of a one-base deletion in the Ugt1a gene ameliorates hyperbilirubinemia in Crigler-Najjar syndrome mice.
Bortolussi G, Iaconcig A, Canarutto G, Porro F, Ferrucci F, Galletta C, Díaz-Muñoz C, Rawat V, De Caneva A, Olajide OJ, Zentilin L, Piazza S, Bočkor L, Muro AF. Bortolussi G, et al. Among authors: ferrucci f. Mol Ther Methods Clin Dev. 2023 Nov 19;31:101161. doi: 10.1016/j.omtm.2023.101161. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 38094199 Free PMC article.