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Page 1
UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.
Hjerpe R, Bett JS, Keuss MJ, Solovyova A, McWilliams TG, Johnson C, Sahu I, Varghese J, Wood N, Wightman M, Osborne G, Bates GP, Glickman MH, Trost M, Knebel A, Marchesi F, Kurz T. Hjerpe R, et al. Cell. 2016 Aug 11;166(4):935-949. doi: 10.1016/j.cell.2016.07.001. Epub 2016 Jul 28. Cell. 2016. PMID: 27477512 Free PMC article.
Alternative UPS drug targets upstream the 26S proteasome.
Hjerpe R, Rodríguez MS. Hjerpe R, et al. Int J Biochem Cell Biol. 2008;40(6-7):1126-40. doi: 10.1016/j.biocel.2007.11.021. Epub 2007 Dec 8. Int J Biochem Cell Biol. 2008. PMID: 18203645 Review.
Tetramerization-defects of p53 result in aberrant ubiquitylation and transcriptional activity.
Lang V, Pallara C, Zabala A, Lobato-Gil S, Lopitz-Otsoa F, Farrás R, Hjerpe R, Torres-Ramos M, Zabaleta L, Blattner C, Hay RT, Barrio R, Carracedo A, Fernandez-Recio J, Rodríguez MS, Aillet F. Lang V, et al. Among authors: hjerpe r. Mol Oncol. 2014 Jul;8(5):1026-42. doi: 10.1016/j.molonc.2014.04.002. Epub 2014 Apr 13. Mol Oncol. 2014. PMID: 24816189 Free PMC article.
17 results