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Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice.
Moya IM, Castaldo SA, Van den Mooter L, Soheily S, Sansores-Garcia L, Jacobs J, Mannaerts I, Xie J, Verboven E, Hillen H, Algueró-Nadal A, Karaman R, Van Haele M, Kowalczyk W, De Waegeneer M, Verhulst S, Karras P, van Huffel L, Zender L, Marine JC, Roskams T, Johnson R, Aerts S, van Grunsven LA, Halder G. Moya IM, et al. Among authors: jacobs j. Science. 2019 Nov 22;366(6468):1029-1034. doi: 10.1126/science.aaw9886. Science. 2019. PMID: 31754005
dachshund Potentiates Hedgehog Signaling during Drosophila Retinogenesis.
Brás-Pereira C, Potier D, Jacobs J, Aerts S, Casares F, Janody F. Brás-Pereira C, et al. Among authors: jacobs j. PLoS Genet. 2016 Jul 21;12(7):e1006204. doi: 10.1371/journal.pgen.1006204. eCollection 2016 Jul. PLoS Genet. 2016. PMID: 27442438 Free PMC article.
Hippo Reprograms the Transcriptional Response to Ras Signaling.
Pascual J, Jacobs J, Sansores-Garcia L, Natarajan M, Zeitlinger J, Aerts S, Halder G, Hamaratoglu F. Pascual J, et al. Among authors: jacobs j. Dev Cell. 2017 Sep 25;42(6):667-680.e4. doi: 10.1016/j.devcel.2017.08.013. Dev Cell. 2017. PMID: 28950103 Free article.
The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes.
Jacobs J, Atkins M, Davie K, Imrichova H, Romanelli L, Christiaens V, Hulselmans G, Potier D, Wouters J, Taskiran II, Paciello G, González-Blas CB, Koldere D, Aibar S, Halder G, Aerts S. Jacobs J, et al. Nat Genet. 2018 Jul;50(7):1011-1020. doi: 10.1038/s41588-018-0140-x. Epub 2018 Jun 4. Nat Genet. 2018. PMID: 29867222 Free PMC article.