Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Ramakrishnan SK, Zhang H, Ma X, Jung I, Schwartz AJ, Triner D, Devenport SN, Das NK, Xue X, Zeng MY, Hu Y, Mortensen RM, Greenson JK, Cascalho M, Wobus CE, Colacino JA, Nunez G, Rui L, Shah YM.
Ramakrishnan SK, et al. Among authors: wobus ce.
Nat Commun. 2019 Feb 8;10(1):660. doi: 10.1038/s41467-019-08581-8.
Nat Commun. 2019.
PMID: 30737385
Free PMC article.
The function of M-cells in systemic inflammatory responses are still unclear. Here we show that epithelial non-canonical NFkB signaling mediated by NFkB-inducing kinase (NIK) is highly active in intestinal lymphoid follicles, and is required for M-cell maintenance. …
The function of M-cells in systemic inflammatory responses are still unclear. Here we show that epithelial non-canonical NFkB signali …