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Page 1
Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer.
Nat Genet. 2020 Oct;52(10):1011-1017. doi: 10.1038/s41588-020-0681-7. Epub 2020 Aug 31.
Nat Genet. 2020.
PMID: 32868907
Free PMC article.
SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1.
Wang Z, Petricca J, Liu M, Zhang S, Chen S, Li M, Besschetnova A, Patalano S, Venkataramani K, Siegfried KR, Macoska JA, Han D, Gao S, Vedadi M, Arrowsmith CH, He HH, Cai C.
Wang Z, et al. Among authors: besschetnova a.
Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2220472120. doi: 10.1073/pnas.2220472120. Epub 2023 Aug 7.
Proc Natl Acad Sci U S A. 2023.
PMID: 37549269
Free PMC article.
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Demethylation of EHMT1/GLP Protein Reprograms Its Transcriptional Activity and Promotes Prostate Cancer Progression.
Besschetnova A, Han W, Liu M, Gao Y, Li M, Wang Z, Labaf M, Patalano S, Venkataramani K, Muriph RE, Macoska JA, Siegfried KR, Evans J, Balk SP, Gao S, Han D, Cai C.
Besschetnova A, et al.
Cancer Res Commun. 2023 Aug 31;3(8):1716-1730. doi: 10.1158/2767-9764.CRC-23-0208. eCollection 2023 Aug.
Cancer Res Commun. 2023.
PMID: 37663929
Free PMC article.
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Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activating distinct transcriptional programs.
Han D, Labaf M, Zhao Y, Owiredu J, Zhang S, Patel K, Venkataramani K, Steinfeld JS, Han W, Li M, Liu M, Wang Z, Besschetnova A, Patalano S, Mulhearn MJ, Macoska JA, Yuan X, Balk SP, Nelson PS, Plymate SR, Gao S, Siegfried KR, Liu R, Stangis MM, Foxa G, Czernik PJ, Williams BO, Zarringhalam K, Li X, Cai C.
Han D, et al. Among authors: besschetnova a.
J Clin Invest. 2024 Apr 30;134(11):e168649. doi: 10.1172/JCI168649. Online ahead of print.
J Clin Invest. 2024.
PMID: 38687617
Free PMC article.
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RB1 loss in castration-resistant prostate cancer confers vulnerability to LSD1 inhibition.
Han W, Liu M, Han D, Li M, Toure AA, Wang Z, Besschetnova A, Patalano S, Macoska JA, Gao S, He HH, Cai C.
Han W, et al. Among authors: besschetnova a.
Oncogene. 2022 Feb;41(6):852-864. doi: 10.1038/s41388-021-02135-3. Epub 2022 Jan 3.
Oncogene. 2022.
PMID: 34975152
Free PMC article.
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Exploiting the tumor-suppressive activity of the androgen receptor by CDK4/6 inhibition in castration-resistant prostate cancer.
Han W, Liu M, Han D, Toure AA, Li M, Besschetnova A, Wang Z, Patalano S, Macoska JA, Lam HM, Corey E, He HH, Gao S, Balk SP, Cai C.
Han W, et al. Among authors: besschetnova a.
Mol Ther. 2022 Apr 6;30(4):1628-1644. doi: 10.1016/j.ymthe.2022.01.039. Epub 2022 Feb 2.
Mol Ther. 2022.
PMID: 35121110
Free PMC article.
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