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Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non-small cell lung cancer (NSCLC) through inhibition of HIF-1α.
Biziotis OD, Tsakiridis EE, Ali A, Ahmadi E, Wu J, Wang S, Mekhaeil B, Singh K, Menjolian G, Farrell T, Abdulkarim B, Sur RK, Mesci A, Ellis P, Berg T, Bramson JL, Muti P, Steinberg GR, Tsakiridis T. Biziotis OD, et al. Mol Oncol. 2023 Nov;17(11):2235-2256. doi: 10.1002/1878-0261.13508. Epub 2023 Aug 27. Mol Oncol. 2023. PMID: 37584455 Free PMC article.
18F-DCFPyL (PSMA) PET as a radiotherapy response assessment tool in metastatic prostate cancer.
Mesci A, Ahmadi E, Ali A, Gouran-Savadkoohi M, Evelyn Tsakiridis E, Biziotis OD, Chow T, Kapoor A, Sur M, Steinberg GR, Liu S, Zukotynski K, Tsakiridis T. Mesci A, et al. Among authors: biziotis od. Clin Transl Radiat Oncol. 2023 Jan 18;39:100583. doi: 10.1016/j.ctro.2023.100583. eCollection 2023 Mar. Clin Transl Radiat Oncol. 2023. PMID: 36713978 Free PMC article.
Combined metformin-salicylate treatment provides improved anti-tumor activity and enhanced radiotherapy response in prostate cancer; drug synergy at clinically relevant doses.
Tsakiridis EE, Broadfield L, Marcinko K, Biziotis OD, Ali A, Mekhaeil B, Ahmadi E, Singh K, Mesci A, Zacharidis PG, Anagnostopoulos AE, Berg T, Muti P, Steinberg GR, Tsakiridis T. Tsakiridis EE, et al. Among authors: biziotis od. Transl Oncol. 2021 Nov;14(11):101209. doi: 10.1016/j.tranon.2021.101209. Epub 2021 Aug 31. Transl Oncol. 2021. PMID: 34479029 Free PMC article.