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Page 1
Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retina.
Curr Biol. 2023 Sep 25;33(18):3805-3820.e7. doi: 10.1016/j.cub.2023.07.031. Epub 2023 Aug 15.
Curr Biol. 2023.
PMID: 37586372
Complement activation, lipid metabolism, and mitochondrial injury: Converging pathways in age-related macular degeneration.
Tan LX, Germer CJ, La Cunza N, Lakkaraju A.
Tan LX, et al. Among authors: la cunza n.
Redox Biol. 2020 Oct;37:101781. doi: 10.1016/j.redox.2020.101781. Epub 2020 Nov 2.
Redox Biol. 2020.
PMID: 33162377
Free PMC article.
Review.
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Mitochondria-dependent phase separation of disease-relevant proteins drives pathological features of age-related macular degeneration.
La Cunza N, Tan LX, Thamban T, Germer CJ, Rathnasamy G, Toops KA, Lakkaraju A.
La Cunza N, et al.
JCI Insight. 2021 May 10;6(9):e142254. doi: 10.1172/jci.insight.142254.
JCI Insight. 2021.
PMID: 33822768
Free PMC article.
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Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis.
Gifford GB, Demitrack ES, Keeley TM, Tam A, La Cunza N, Dedhia PH, Spence JR, Simeone DM, Saotome I, Louvi A, Siebel CW, Samuelson LC.
Gifford GB, et al. Among authors: la cunza n.
Gut. 2017 Jun;66(6):1001-1011. doi: 10.1136/gutjnl-2015-310811. Epub 2016 Mar 1.
Gut. 2017.
PMID: 26933171
Free PMC article.
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Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration.
Kaur G, Tan LX, Rathnasamy G, La Cunza N, Germer CJ, Toops KA, Fernandes M, Blenkinsop TA, Lakkaraju A.
Kaur G, et al. Among authors: la cunza n.
Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):9014-9019. doi: 10.1073/pnas.1805039115. Epub 2018 Aug 20.
Proc Natl Acad Sci U S A. 2018.
PMID: 30126999
Free PMC article.
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