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The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis.
Miyamoto K, Sujino T, Harada Y, Ashida H, Yoshimatsu Y, Yonemoto Y, Nemoto Y, Tomura M, Melhem H, Niess JH, Suzuki T, Suzuki T, Suzuki S, Koda Y, Okamoto R, Mikami Y, Teratani T, Tanaka KF, Yoshimura A, Sato T, Kanai T. Miyamoto K, et al. Among authors: yonemoto y. Cell Rep. 2023 Aug 29;42(8):113005. doi: 10.1016/j.celrep.2023.113005. Epub 2023 Aug 16. Cell Rep. 2023. PMID: 37590143 Free article.
Lead generation from N-[benzyl(4-phenylbutyl)carbamoyl]amino acid as a novel LPA1 antagonist for the treatment of systemic sclerosis.
Kobayashi Y, Uneuchi F, Naruse T, Matsuda D, Okumura-Kitajima L, Kajiyama H, Wada R, Yonemoto Y, Nakano K, Toki H, Kamigaso S, Yamagishi J, Tokura S, Kakinuma H, Kuroda S. Kobayashi Y, et al. Among authors: yonemoto y. Eur J Med Chem. 2023 Nov 15;260:115749. doi: 10.1016/j.ejmech.2023.115749. Epub 2023 Aug 20. Eur J Med Chem. 2023. PMID: 37639822
Intraepithelial Lymphocytes Suppress Intestinal Tumor Growth by Cell-to-Cell Contact via CD103/E-Cadherin Signal.
Morikawa R, Nemoto Y, Yonemoto Y, Tanaka S, Takei Y, Oshima S, Nagaishi T, Tsuchiya K, Nozaki K, Mizutani T, Nakamura T, Watanabe M, Okamoto R. Morikawa R, et al. Among authors: yonemoto y. Cell Mol Gastroenterol Hepatol. 2021;11(5):1483-1503. doi: 10.1016/j.jcmgh.2021.01.014. Epub 2021 Jan 28. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33515805 Free PMC article.
Apelin expression is downregulated in T cells in a murine model of chronic colitis.
Yamada D, Kojima Y, Hosoya A, Suzuki M, Watabe T, Inoue T, Tsugawa N, Asakawa T, Yonemoto Y, Onizawa M, Nemoto Y, Oshima S, Shimonaka M, Kuba K, Ishida J, Fukamizu A, Penninger JM, Watanabe M, Okamoto R, Nagaishi T. Yamada D, et al. Among authors: yonemoto y. Biochem Biophys Res Commun. 2023 Mar 5;647:72-79. doi: 10.1016/j.bbrc.2023.01.068. Epub 2023 Jan 21. Biochem Biophys Res Commun. 2023. PMID: 36731336
Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment.
Ochiai N, Nakachi Y, Yokoo T, Ichihara T, Eriksson T, Yonemoto Y, Kato T, Ogata H, Fujimoto N, Kobayashi Y, Udagawa N, Kaku S, Ueki T, Okazaki Y, Takahashi N, Suda T. Ochiai N, et al. Among authors: yonemoto y. Commun Biol. 2019 Mar 1;2:86. doi: 10.1038/s42003-019-0334-5. eCollection 2019. Commun Biol. 2019. PMID: 30854478 Free PMC article.