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Year Number of Results
2019 3
2020 4
2021 3
2023 1
2024 2

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13 results

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Page 1
FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy.
Chan JD, Scheffler CM, Munoz I, Sek K, Lee JN, Huang YK, Yap KM, Saw NYL, Li J, Chen AXY, Chan CW, Derrick EB, Todd KL, Tong J, Dunbar PA, Li J, Hoang TX, de Menezes MN, Petley EV, Kim JS, Nguyen D, Leung PSK, So J, Deguit C, Zhu J, House IG, Kats LM, Scott AM, Solomon BJ, Harrison SJ, Oliaro J, Parish IA, Quinn KM, Neeson PJ, Slaney CY, Lai J, Beavis PA, Darcy PK. Chan JD, et al. Nature. 2024 May;629(8010):201-210. doi: 10.1038/s41586-024-07242-1. Epub 2024 Apr 10. Nature. 2024. PMID: 38600376 Free PMC article.
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
House IG, Derrick EB, Sek K, Chen AXY, Li J, Lai J, Todd KL, Munoz I, Michie J, Chan CW, Huang YK, Chan JD, Petley EV, Tong J, Nguyen D, Engel S, Savas P, Hogg SJ, Vervoort SJ, Kearney CJ, Burr ML, Lam EYN, Gilan O, Bedoui S, Johnstone RW, Dawson MA, Loi S, Darcy PK, Beavis PA. House IG, et al. Among authors: chan jd. Cell Rep. 2023 Aug 29;42(8):113014. doi: 10.1016/j.celrep.2023.113014. Epub 2023 Aug 21. Cell Rep. 2023. PMID: 37605534 Free article.
MAIT cells regulate NK cell-mediated tumor immunity.
Petley EV, Koay HF, Henderson MA, Sek K, Todd KL, Keam SP, Lai J, House IG, Li J, Zethoven M, Chen AXY, Oliver AJ, Michie J, Freeman AJ, Giuffrida L, Chan JD, Pizzolla A, Mak JYW, McCulloch TR, Souza-Fonseca-Guimaraes F, Kearney CJ, Millen R, Ramsay RG, Huntington ND, McCluskey J, Oliaro J, Fairlie DP, Neeson PJ, Godfrey DI, Beavis PA, Darcy PK. Petley EV, et al. Among authors: chan jd. Nat Commun. 2021 Aug 6;12(1):4746. doi: 10.1038/s41467-021-25009-4. Nat Commun. 2021. PMID: 34362900 Free PMC article.
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
House IG, Derrick EB, Sek K, Chen AXY, Li J, Lai J, Todd KL, Munoz I, Michie J, Chan CW, Huang YK, Chan JD, Petley EV, Tong J, Nguyen D, Engel S, Savas P, Hogg SJ, Vervoort SJ, Kearney CJ, Burr ML, Lam EYN, Gilan O, Bedoui S, Johnstone RW, Dawson MA, Loi S, Darcy PK, Beavis PA. House IG, et al. Among authors: chan jd. Cell Rep. 2024 Feb 27;43(2):113793. doi: 10.1016/j.celrep.2024.113793. Epub 2024 Feb 5. Cell Rep. 2024. PMID: 38324452 Free article. No abstract available.
Tissue-specific tumor microenvironments influence responses to immunotherapies.
Oliver AJ, Davey AS, Keam SP, Mardiana S, Chan JD, von Scheidt B, Beavis PA, House IG, Van Audernaerde JR, Darcy PK, Kershaw MH, Slaney CY. Oliver AJ, et al. Among authors: chan jd. Clin Transl Immunology. 2019 Nov 21;8(11):e1094. doi: 10.1002/cti2.1094. eCollection 2019. Clin Transl Immunology. 2019. PMID: 31768254 Free PMC article.
Enterotoxins can support CAR T cells against solid tumors.
von Scheidt B, Wang M, Oliver AJ, Chan JD, Jana MK, Ali AI, Clow F, Fraser JD, Quinn KM, Darcy PK, Kershaw MH, Slaney CY. von Scheidt B, et al. Among authors: chan jd. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25229-25235. doi: 10.1073/pnas.1904618116. Epub 2019 Nov 25. Proc Natl Acad Sci U S A. 2019. PMID: 31767744 Free PMC article.
13 results