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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
House IG, Derrick EB, Sek K, Chen AXY, Li J, Lai J, Todd KL, Munoz I, Michie J, Chan CW, Huang YK, Chan JD, Petley EV, Tong J, Nguyen D, Engel S, Savas P, Hogg SJ, Vervoort SJ, Kearney CJ, Burr ML, Lam EYN, Gilan O, Bedoui S, Johnstone RW, Dawson MA, Loi S, Darcy PK, Beavis PA. House IG, et al. Among authors: engel s. Cell Rep. 2023 Aug 29;42(8):113014. doi: 10.1016/j.celrep.2023.113014. Epub 2023 Aug 21. Cell Rep. 2023. PMID: 37605534 Free article.
CD4+ T cell immunity against cutaneous melanoma encompasses multifaceted MHC II-dependent responses.
Bawden EG, Wagner T, Schröder J, Effern M, Hinze D, Newland L, Attrill GH, Lee AR, Engel S, Freestone D, de Lima Moreira M, Gressier E, McBain N, Bachem A, Haque A, Dong R, Ferguson AL, Edwards JJ, Ferguson PM, Scolyer RA, Wilmott JS, Jewell CM, Brooks AG, Gyorki DE, Palendira U, Bedoui S, Waithman J, Hochheiser K, Hölzel M, Gebhardt T. Bawden EG, et al. Among authors: engel s. Sci Immunol. 2024 Jan 19;9(91):eadi9517. doi: 10.1126/sciimmunol.adi9517. Epub 2024 Jan 19. Sci Immunol. 2024. PMID: 38241401
CD4+ T cell immunity to Salmonella is transient in the circulation.
Peres NG, Wang N, Whitney P, Engel S, Shreenivas MM, Comerford I, Hocking DM, Erazo AB, Förster I, Kupz A, Gebhardt T, McColl SR, McSorley SJ, Bedoui S, Strugnell RA. Peres NG, et al. Among authors: engel s. PLoS Pathog. 2021 Oct 25;17(10):e1010004. doi: 10.1371/journal.ppat.1010004. eCollection 2021 Oct. PLoS Pathog. 2021. PMID: 34695149 Free PMC article.
Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection.
Doerflinger M, Deng Y, Whitney P, Salvamoser R, Engel S, Kueh AJ, Tai L, Bachem A, Gressier E, Geoghegan ND, Wilcox S, Rogers KL, Garnham AL, Dengler MA, Bader SM, Ebert G, Pearson JS, De Nardo D, Wang N, Yang C, Pereira M, Bryant CE, Strugnell RA, Vince JE, Pellegrini M, Strasser A, Bedoui S, Herold MJ. Doerflinger M, et al. Among authors: engel s. Immunity. 2020 Sep 15;53(3):533-547.e7. doi: 10.1016/j.immuni.2020.07.004. Epub 2020 Jul 30. Immunity. 2020. PMID: 32735843 Free PMC article.
MiR-21 is required for efficient kidney regeneration in fish.
Hoppe B, Pietsch S, Franke M, Engel S, Groth M, Platzer M, Englert C. Hoppe B, et al. Among authors: engel s. BMC Dev Biol. 2015 Nov 17;15:43. doi: 10.1186/s12861-015-0089-2. BMC Dev Biol. 2015. PMID: 26577279 Free PMC article.
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
House IG, Derrick EB, Sek K, Chen AXY, Li J, Lai J, Todd KL, Munoz I, Michie J, Chan CW, Huang YK, Chan JD, Petley EV, Tong J, Nguyen D, Engel S, Savas P, Hogg SJ, Vervoort SJ, Kearney CJ, Burr ML, Lam EYN, Gilan O, Bedoui S, Johnstone RW, Dawson MA, Loi S, Darcy PK, Beavis PA. House IG, et al. Among authors: engel s. Cell Rep. 2024 Feb 27;43(2):113793. doi: 10.1016/j.celrep.2024.113793. Epub 2024 Feb 5. Cell Rep. 2024. PMID: 38324452 Free article. No abstract available.