Abstract
Paeoniflorin (1), isolated from the methanol extract of Paeonia lactiflora, showed a lowering effect on cholesterol level in the experimentally-induced hyperlipidemic rats. Paeoniflorin showed a significantly lowering effect of total cholesterol, LDL and triglyceride levels compared with the control group at the dose of 200 and 400 mg/kg, p.o. once a day for 4 weeks.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Administration, Oral
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Animals
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Benzoates / administration & dosage
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Benzoates / pharmacology*
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Benzoates / therapeutic use
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Bridged-Ring Compounds / administration & dosage
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Bridged-Ring Compounds / pharmacology*
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Bridged-Ring Compounds / therapeutic use
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Cholesterol / blood
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Cholesterol, LDL / blood
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Cholesterol, LDL / drug effects
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Dose-Response Relationship, Drug
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Glucosides / administration & dosage
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Glucosides / pharmacology*
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Glucosides / therapeutic use
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Hyperlipidemias / prevention & control*
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Hypolipidemic Agents / administration & dosage
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Hypolipidemic Agents / pharmacology*
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Hypolipidemic Agents / therapeutic use
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Male
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Monoterpenes
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Paeonia*
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Phytotherapy*
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology
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Plant Extracts / therapeutic use
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Plant Roots
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Rats
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Rats, Wistar
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Triglycerides / blood
Substances
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Benzoates
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Bridged-Ring Compounds
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Cholesterol, LDL
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Glucosides
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Hypolipidemic Agents
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Monoterpenes
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Plant Extracts
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Triglycerides
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peoniflorin
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Cholesterol