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Did you mean david st jean[Author] (31 results)?
STX-478, a Mutant-Selective, Allosteric PI3Kα Inhibitor Spares Metabolic Dysfunction and Improves Therapeutic Response in PI3Kα-Mutant Xenografts.
Buckbinder L, St Jean DJ Jr, Tieu T, Ladd B, Hilbert B, Wang W, Alltucker JT, Manimala S, Kryukov GV, Brooijmans N, Dowdell G, Jonsson P, Huff M, Guzman-Perez A, Jackson EL, Goncalves MD, Stuart DD. Buckbinder L, et al. Among authors: st jean dj jr. Cancer Discov. 2023 Nov 1;13(11):2432-2447. doi: 10.1158/2159-8290.CD-23-0396. Cancer Discov. 2023. PMID: 37623743 Free PMC article.
Mitigating heterocycle metabolism in drug discovery.
St Jean DJ Jr, Fotsch C. St Jean DJ Jr, et al. J Med Chem. 2012 Jul 12;55(13):6002-20. doi: 10.1021/jm300343m. Epub 2012 May 7. J Med Chem. 2012. PMID: 22533875 Review. No abstract available.
Nonracemic synthesis of GK-GKRP disruptor AMG-3969.
Bourbeau MP, Ashton KS, Yan J, St Jean DJ Jr. Bourbeau MP, et al. Among authors: st jean dj jr. J Org Chem. 2014 Apr 18;79(8):3684-7. doi: 10.1021/jo500336e. Epub 2014 Apr 10. J Org Chem. 2014. PMID: 24678849
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors.
Lloyd DJ, St Jean DJ Jr, Kurzeja RJ, Wahl RC, Michelsen K, Cupples R, Chen M, Wu J, Sivits G, Helmering J, Komorowski R, Ashton KS, Pennington LD, Fotsch C, Vazir M, Chen K, Chmait S, Zhang J, Liu L, Norman MH, Andrews KL, Bartberger MD, Van G, Galbreath EJ, Vonderfecht SL, Wang M, Jordan SR, Véniant MM, Hale C. Lloyd DJ, et al. Among authors: st jean dj jr. Nature. 2013 Dec 19;504(7480):437-40. doi: 10.1038/nature12724. Epub 2013 Nov 13. Nature. 2013. PMID: 24226772
Piperidine amides as 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.
Flyrén K, Bergquist LO, Castro VM, Fotsch C, Johansson L, St Jean DJ Jr, Sutin L, Williams M. Flyrén K, et al. Among authors: st jean dj jr. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3421-5. doi: 10.1016/j.bmcl.2007.03.083. Epub 2007 Mar 30. Bioorg Med Chem Lett. 2007. PMID: 17442567
Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors.
Wurz RP, Pettus LH, Ashton K, Brown J, Chen JJ, Herberich B, Hong FT, Hu-Harrington E, Nguyen T, St Jean DJ Jr, Tadesse S, Bauer D, Kubryk M, Zhan J, Cooke K, Mitchell P, Andrews KL, Hsieh F, Hickman D, Kalyanaraman N, Wu T, Reid DL, Lobenhofer EK, Andrews DA, Everds N, Guzman R, Parsons AT, Hedley SJ, Tedrow J, Thiel OR, Potter M, Radinsky R, Beltran PJ, Tasker AS. Wurz RP, et al. Among authors: st jean dj jr. ACS Med Chem Lett. 2015 Jul 27;6(9):987-92. doi: 10.1021/acsmedchemlett.5b00193. eCollection 2015 Sep 10. ACS Med Chem Lett. 2015. PMID: 26396685 Free PMC article.
32 results