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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2010 3
2011 2
2012 3
2013 2
2014 6
2015 2
2016 2
2017 3
2018 3
2019 2
2020 3
2021 4
2022 4
2023 2
2024 3

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42 results

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Page 1
STX-478, a Mutant-Selective, Allosteric PI3Kα Inhibitor Spares Metabolic Dysfunction and Improves Therapeutic Response in PI3Kα-Mutant Xenografts.
Buckbinder L, St Jean DJ Jr, Tieu T, Ladd B, Hilbert B, Wang W, Alltucker JT, Manimala S, Kryukov GV, Brooijmans N, Dowdell G, Jonsson P, Huff M, Guzman-Perez A, Jackson EL, Goncalves MD, Stuart DD. Buckbinder L, et al. Among authors: wang w. Cancer Discov. 2023 Nov 1;13(11):2432-2447. doi: 10.1158/2159-8290.CD-23-0396. Cancer Discov. 2023. PMID: 37623743 Free PMC article.
Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
Tichenor MS, Wiener JJM, Rao NL, Bacani GM, Wei J, Pooley Deckhut C, Barbay JK, Kreutter KD, Chang L, Clancy KW, Murrey HE, Wang W, Ahn K, Huber M, Rex E, Coe KJ, Wu J, Rui H, Sepassi K, Gaudiano M, Bekkers M, Cornelissen I, Packman K, Seierstad M, Xiouras C, Bembenek SD, Alexander R, Milligan C, Balasubramanian S, Lebsack AD, Venable JD, Philippar U, Edwards JP, Hirst G. Tichenor MS, et al. Among authors: wang w. J Med Chem. 2022 Nov 10;65(21):14326-14336. doi: 10.1021/acs.jmedchem.2c01026. Epub 2022 Oct 31. J Med Chem. 2022. PMID: 36314537
Sintilimab Plus Apatinib and Chemotherapy as Second‑/Third-Line treatment for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: a prospective, Single-Arm, phase II trial.
Zhang L, Wang W, Ge S, Li H, Bai M, Duan J, Yang Y, Ning T, Liu R, Wang X, Ji Z, Wang F, Zhang H, Ba Y, Deng T. Zhang L, et al. Among authors: wang w. BMC Cancer. 2023 Mar 5;23(1):211. doi: 10.1186/s12885-023-10661-4. BMC Cancer. 2023. PMID: 36872337 Free PMC article. Clinical Trial.
Identification of Two Non-Peptidergic Small Molecule Inhibitors of CBX2 Binding to K27 Trimethylated Oligonucleosomes.
Lercher L, Simon N, Bergmann A, Tauchert M, Bochmann D, Bashir T, Neuefeind T, Riley D, Danna B, Krawczuk P, Pande V, Patrick A, Steele R, Wang W, Rupnow B, Tummino P, Sharma S, Finley M. Lercher L, et al. Among authors: wang w. SLAS Discov. 2022 Jul;27(5):306-313. doi: 10.1016/j.slasd.2022.04.003. Epub 2022 May 2. SLAS Discov. 2022. PMID: 35513262 Free article.
A carboxylic acid isostere screen of the DHODH inhibitor Brequinar.
DeRatt LG, Christine Pietsch E, Tanner A, Shaffer P, Jacoby E, Wang W, Kazmi F, Zhang X, Attar RM, Edwards JP, Kuduk SD. DeRatt LG, et al. Among authors: wang w. Bioorg Med Chem Lett. 2020 Nov 15;30(22):127589. doi: 10.1016/j.bmcl.2020.127589. Epub 2020 Sep 29. Bioorg Med Chem Lett. 2020. PMID: 33007394
42 results