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Page 1
Novel insights into double-stranded RNA-mediated immunopathology.
Nat Rev Immunol. 2024 Apr;24(4):235-249. doi: 10.1038/s41577-023-00940-3. Epub 2023 Sep 26.
Nat Rev Immunol. 2024.
PMID: 37752355
Review.
ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation.
de Reuver R, Verdonck S, Dierick E, Nemegeer J, Hessmann E, Ahmad S, Jans M, Blancke G, Van Nieuwerburgh F, Botzki A, Vereecke L, van Loo G, Declercq W, Hur S, Vandenabeele P, Maelfait J.
de Reuver R, et al.
Nature. 2022 Jul;607(7920):784-789. doi: 10.1038/s41586-022-04974-w. Epub 2022 Jul 20.
Nature. 2022.
PMID: 35859175
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Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation.
Devos M, Tanghe G, Gilbert B, Dierick E, Verheirstraeten M, Nemegeer J, de Reuver R, Lefebvre S, De Munck J, Rehwinkel J, Vandenabeele P, Declercq W, Maelfait J.
Devos M, et al. Among authors: de reuver r.
J Exp Med. 2020 Jul 6;217(7):e20191913. doi: 10.1084/jem.20191913.
J Exp Med. 2020.
PMID: 32315377
Free PMC article.
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ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation.
de Reuver R, Dierick E, Wiernicki B, Staes K, Seys L, De Meester E, Muyldermans T, Botzki A, Lambrecht BN, Van Nieuwerburgh F, Vandenabeele P, Maelfait J.
de Reuver R, et al.
Cell Rep. 2021 Aug 10;36(6):109500. doi: 10.1016/j.celrep.2021.109500.
Cell Rep. 2021.
PMID: 34380029
Free article.
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