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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 2
1974 1
1977 1
1978 2
1979 2
1982 1
1983 2
1984 4
1985 1
1986 4
1987 9
1988 9
1989 14
1990 21
1991 17
1992 35
1993 33
1994 38
1995 35
1996 48
1997 56
1998 51
1999 83
2000 93
2001 100
2002 125
2003 170
2004 181
2005 227
2006 268
2007 301
2008 396
2009 437
2010 538
2011 654
2012 768
2013 865
2014 1138
2015 1240
2016 1281
2017 1400
2018 1718
2019 2024
2020 2316
2021 2567
2022 2789
2023 2787
2024 1512

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23,250 results

Results by year

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Page 1
Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA.
Zhang LS, Liu C, Ma H, Dai Q, Sun HL, Luo G, Zhang Z, Zhang L, Hu L, Dong X, He C. Zhang LS, et al. Among authors: hu l. Mol Cell. 2019 Jun 20;74(6):1304-1316.e8. doi: 10.1016/j.molcel.2019.03.036. Epub 2019 Apr 25. Mol Cell. 2019. PMID: 31031084 Free PMC article.
Here, we show the presence of internal m(7)G sites within mammalian mRNA. We then performed transcriptome-wide profiling of internal m(7)G methylome using m(7)G-MeRIP sequencing (MeRIP-seq). ...This base-resolution m(7)G-seq enabled transcriptome-wide …
Here, we show the presence of internal m(7)G sites within mammalian mRNA. We then performed transcriptome-wide profiling of internal …
Conserved class B GPCR activation by a biased intracellular agonist.
Zhao LH, He Q, Yuan Q, Gu Y, He X, Shan H, Li J, Wang K, Li Y, Hu W, Wu K, Shen J, Xu HE. Zhao LH, et al. Among authors: hu w. Nature. 2023 Sep;621(7979):635-641. doi: 10.1038/s41586-023-06467-w. Epub 2023 Jul 31. Nature. 2023. PMID: 37524305
Class B G-protein-coupled receptors (GPCRs), including glucagon-like peptide 1 receptor (GLP1R) and parathyroid hormone 1 receptor (PTH1R), are important drug targets(1-5). ...Here we report the high-resolution structure of human PTH1R in complex with the stimulatory G
Class B G-protein-coupled receptors (GPCRs), including glucagon-like peptide 1 receptor (GLP1R) and parathyroid hormone 1 receptor (P …
Therapeutic potential of bacteriophage endolysins for infections caused by Gram-positive bacteria.
Liu H, Hu Z, Li M, Yang Y, Lu S, Rao X. Liu H, et al. Among authors: hu z. J Biomed Sci. 2023 Apr 26;30(1):29. doi: 10.1186/s12929-023-00919-1. J Biomed Sci. 2023. PMID: 37101261 Free PMC article. Review.
Gram-positive (G(+)) bacterial infection is a great burden to both healthcare and community medical resources. As a result of the increasing prevalence of multidrug-resistant G(+) bacteria such as methicillin-resistant Staphylococcus aureus (MRSA), novel antimicrobi …
Gram-positive (G(+)) bacterial infection is a great burden to both healthcare and community medical resources. As a result of the inc …
Both chimpanzee adenovirus-vectored and DNA vaccines induced long-term immunity against Nipah virus infection.
Lu M, Yao Y, Zhang X, Liu H, Gao G, Peng Y, Chen M, Zhao J, Zhang X, Yin C, Guo W, Yang P, Hu X, Rao J, Li E, Chen T, Chiu S, Wong G, Yuan Z, Lan J, Shan C. Lu M, et al. Among authors: hu x. NPJ Vaccines. 2023 Nov 4;8(1):170. doi: 10.1038/s41541-023-00762-3. NPJ Vaccines. 2023. PMID: 37925490 Free PMC article.
Here, a recombinant chimpanzee adenovirus-based vaccine (AdC68-G) and a DNA vaccine (DNA-G) were developed by expressing the codon-optimized full-length glycoprotein (G) of NiV. ...Importantly, the neutralizing antibody titers were maintained for up to 68 wee …
Here, a recombinant chimpanzee adenovirus-based vaccine (AdC68-G) and a DNA vaccine (DNA-G) were developed by expressing the c …
Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Shen Q, Tang X, Wen X, Cheng S, Xiao P, Zang SK, Shen DD, Jiang L, Zheng Y, Zhang H, Xu H, Mao C, Zhang M, Hu W, Sun JP, Zhang Y, Chen Z. Shen Q, et al. Among authors: hu w. Adv Sci (Weinh). 2024 Apr 22:e2310120. doi: 10.1002/advs.202310120. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38647423
G-protein-coupled receptors (GPCRs) transmit downstream signals predominantly via G-protein pathways. However, the conformational basis of selective coupling of primary G-protein remains elusive. Histamine receptors H(2)R and H(3)R couple with G(s)- or
G-protein-coupled receptors (GPCRs) transmit downstream signals predominantly via G-protein pathways. However, the conformatio
Flow-mediated vasodilation through mechanosensitive G protein-coupled receptors in endothelial cells.
Hu Y, Chen M, Wang M, Li X. Hu Y, et al. Trends Cardiovasc Med. 2022 Feb;32(2):61-70. doi: 10.1016/j.tcm.2020.12.010. Epub 2021 Jan 3. Trends Cardiovasc Med. 2022. PMID: 33406458 Review.
Researchers have proposed multiple mechanosensors that may be involved in flow-mediated vasodilation (FMD), including G protein-coupled receptors (GPCRs), ion channels, and intercellular junction proteins, among others. However, GPCRs are considered the major mechanosensor …
Researchers have proposed multiple mechanosensors that may be involved in flow-mediated vasodilation (FMD), including G protein-coupl …
Cyano-Rich g-C(3) N(4) in Photochemistry: Design, Applications, and Prospects.
Jing L, Xu Y, Xie M, Li Z, Wu C, Zhao H, Zhong N, Wang J, Wang H, Yan Y, Li H, Hu J. Jing L, et al. Among authors: hu j. Small. 2024 Jan;20(2):e2304404. doi: 10.1002/smll.202304404. Epub 2023 Sep 5. Small. 2024. PMID: 37670529 Review.
Notwithstanding, there is yet a huge knowledge break in the design, preparation, detection, application, and prospect of cyano-rich g-C(3) N(4) . Accordingly, an overall review is arranged to substantially comprehend the research progress and position of cyano-rich g
Notwithstanding, there is yet a huge knowledge break in the design, preparation, detection, application, and prospect of cyano-rich g
Birth weight and subsequent blood pressure: a meta-analysis.
Mu M, Wang SF, Sheng J, Zhao Y, Li HZ, Hu CL, Tao FB. Mu M, et al. Among authors: hu cl. Arch Cardiovasc Dis. 2012 Feb;105(2):99-113. doi: 10.1016/j.acvd.2011.10.006. Epub 2012 Feb 14. Arch Cardiovasc Dis. 2012. PMID: 22424328 Free article. Review.
Among 78 studies reporting on the association between birth weight and subsequent blood pressure, 20 articles (reporting 27 original studies) were eligible for inclusion. Low birth weight (< 2500 g) compared with birth weight greater than 2500 g was associated wi …
Among 78 studies reporting on the association between birth weight and subsequent blood pressure, 20 articles (reporting 27 original studies …
Ginsenoside Rg3 promotes hepatic stellate cell ferroptosis by epigenetically regulating ACSL4 to suppress liver fibrosis progression.
Hu Y, Lang Z, Li X, Lin L, Li Y, Zhang R, Zheng J, Yu Z. Hu Y, et al. Phytomedicine. 2024 Feb;124:155289. doi: 10.1016/j.phymed.2023.155289. Epub 2023 Dec 16. Phytomedicine. 2024. PMID: 38176269
In vitro, G-Rg3 contributed to HSC inactivation, leading to decreased collagen production. ...Moreover, G-Rg3 promoted ACSL4 demethylation and restored its expression. ...
In vitro, G-Rg3 contributed to HSC inactivation, leading to decreased collagen production. ...Moreover, G-Rg3 promoted ACSL4 d …
The effect of granulocyte and granulocyte-macrophage colony stimulating factors on tumor promotion.
Liu Q, Qiao L, Hu P, Deng G, Zhang J, Liang N, Xie J, Zhang J. Liu Q, et al. Among authors: hu p. J BUON. 2017 Jan-Feb;22(1):21-28. J BUON. 2017. PMID: 28365931 Free article. Review.
Thereby, clinicians correct neutropenia induced by chemotherapy or radiation routinely with recombinant G- or GM-CSFs in clinical practice. However, relevant studies found that treatment for cancer patients with adjuvant G-/GM-CSF would occasionally enhance the prog …
Thereby, clinicians correct neutropenia induced by chemotherapy or radiation routinely with recombinant G- or GM-CSFs in clinical pra …
23,250 results
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