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A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages.
Bedard M, van der Niet S, Bernard EM, Babunovic G, Cheng TY, Aylan B, Grootemaat AE, Raman S, Botella L, Ishikawa E, O'Sullivan MP, O'Leary S, Mayfield JA, Buter J, Minnaard AJ, Fortune SM, Murphy LO, Ory DS, Keane J, Yamasaki S, Gutierrez MG, van der Wel N, Moody DB. Bedard M, et al. Among authors: botella l. J Clin Invest. 2023 Mar 15;133(6):e161944. doi: 10.1172/JCI161944. J Clin Invest. 2023. PMID: 36757797 Free PMC article.
An NAD+ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
Freire DM, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V, Cianci M, Tuukkanen A, Boudehen YM, Peixoto A, Botella L, Svergun DI, Schnappinger D, Schneider TR, Genevaux P, de Carvalho LPS, Wilmanns M, Parret AHA, Neyrolles O. Freire DM, et al. Among authors: botella l. Mol Cell. 2019 Mar 21;73(6):1282-1291.e8. doi: 10.1016/j.molcel.2019.01.028. Epub 2019 Feb 18. Mol Cell. 2019. PMID: 30792174 Free PMC article.
Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation.
Queval CJ, Fearns A, Botella L, Smyth A, Schnettger L, Mitermite M, Wooff E, Villarreal-Ramos B, Garcia-Jimenez W, Heunis T, Trost M, Werling D, Salguero FJ, Gordon SV, Gutierrez MG. Queval CJ, et al. Among authors: botella l. PLoS Pathog. 2021 Mar 15;17(3):e1009410. doi: 10.1371/journal.ppat.1009410. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33720986 Free PMC article.
14 results