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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1967 1
1968 1
1970 1
1971 3
1972 1
1973 3
1974 4
1975 17
1976 17
1977 23
1978 19
1979 34
1980 70
1981 111
1982 128
1983 156
1984 189
1985 177
1986 197
1987 229
1988 234
1989 266
1990 291
1991 285
1992 306
1993 324
1994 330
1995 365
1996 407
1997 456
1998 536
1999 594
2000 607
2001 715
2002 659
2003 789
2004 961
2005 962
2006 996
2007 1064
2008 1045
2009 1154
2010 1158
2011 1287
2012 1337
2013 1500
2014 1457
2015 1385
2016 920
2017 746
2018 987
2019 967
2020 1087
2021 1195
2022 1085
2023 947
2024 251
2025 1

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28,071 results

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T cells in the brain inflammation.
Yoshimura A, Ohyagi M, Ito M. Yoshimura A, et al. Among authors: ito m. Adv Immunol. 2023;157:29-58. doi: 10.1016/bs.ai.2022.10.001. Epub 2022 Nov 24. Adv Immunol. 2023. PMID: 37061287 Review.
Additionally, the immune system is involved in various brain diseases including cerebral infarction and neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). In particular, reports related to T cells …
Additionally, the immune system is involved in various brain diseases including cerebral infarction and neurodegenerative diseases such as A …
Memory T cell, exhaustion, and tumor immunity.
Ando M, Ito M, Srirat T, Kondo T, Yoshimura A. Ando M, et al. Among authors: ito m. Immunol Med. 2020 Mar;43(1):1-9. doi: 10.1080/25785826.2019.1698261. Epub 2019 Dec 10. Immunol Med. 2020. PMID: 31822213 Review.
These dysfunctions are associated with altered transcriptional programs and epigenetic regulations and recent studies suggested that NR4a and TOX transcription factors are deeply involved in exhaustion phenotypes. However, an increase the early memory T cells including ste …
These dysfunctions are associated with altered transcriptional programs and epigenetic regulations and recent studies suggested that NR4a an …
Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery.
Ito M, Komai K, Mise-Omata S, Iizuka-Koga M, Noguchi Y, Kondo T, Sakai R, Matsuo K, Nakayama T, Yoshie O, Nakatsukasa H, Chikuma S, Shichita T, Yoshimura A. Ito M, et al. Nature. 2019 Jan;565(7738):246-250. doi: 10.1038/s41586-018-0824-5. Epub 2019 Jan 2. Nature. 2019. PMID: 30602786
In addition to maintaining immune tolerance, FOXP3(+) regulatory T (T(reg)) cells perform specialized functions in tissue homeostasis and remodelling(1,2). However, the characteristics and functions of brain T(reg) cells are not well understood because there …
In addition to maintaining immune tolerance, FOXP3(+) regulatory T (T(reg)) cells perform specialized functions in tissue home …
Alveolar macrophages instruct CD8(+) T cell expansion by antigen cross-presentation in lung.
Kawasaki T, Ikegawa M, Yunoki K, Otani H, Ori D, Ishii KJ, Kuroda E, Takamura S, Kitabatake M, Ito T, Isotani A, Kawai T. Kawasaki T, et al. Among authors: ito t. Cell Rep. 2022 Dec 13;41(11):111828. doi: 10.1016/j.celrep.2022.111828. Cell Rep. 2022. PMID: 36516765 Free article.
Lung CD8(+) memory T cells play central roles in protective immunity to respiratory viruses, such as influenza A virus (IAV). ...AMs highly express interleukin-18 (IL-18), which mediates subsequent formation of CD103(+)CD8(+) resident memory T (T(RM)) cells i …
Lung CD8(+) memory T cells play central roles in protective immunity to respiratory viruses, such as influenza A virus (IAV). ...AMs …
Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells.
Wang B, Iriguchi S, Waseda M, Ueda N, Ueda T, Xu H, Minagawa A, Ishikawa A, Yano H, Ishi T, Ito R, Goto M, Takahashi R, Uemura Y, Hotta A, Kaneko S. Wang B, et al. Among authors: ito r. Nat Biomed Eng. 2021 May;5(5):429-440. doi: 10.1038/s41551-021-00730-z. Epub 2021 May 17. Nat Biomed Eng. 2021. PMID: 34002062
Avoiding the immune rejection of transplanted T cells is central to the success of allogeneic cancer immunotherapies. ...Hypoimmunogenic iPSC-derived T cells may contribute to the creation of off-the-shelf T cell immunotherapies....
Avoiding the immune rejection of transplanted T cells is central to the success of allogeneic cancer immunotherapies. ...Hypoimmunoge …
Single-cell RNA sequencing coupled to TCR profiling of large granular lymphocyte leukemia T cells.
Gao S, Wu Z, Arnold B, Diamond C, Batchu S, Giudice V, Alemu L, Raffo DQ, Feng X, Kajigaya S, Barrett J, Ito S, Young NS. Gao S, et al. Among authors: ito s. Nat Commun. 2022 Apr 11;13(1):1982. doi: 10.1038/s41467-022-29175-x. Nat Commun. 2022. PMID: 35411048 Free PMC article.
T-cell large granular lymphocyte leukemia (T-LGLL) is a lymphoproliferative disease and bone marrow failure syndrome which responds to immunosuppressive therapies. ...Effector memory T cells and loss of T cell receptor (TCR) repertoire diversity are pr …
T-cell large granular lymphocyte leukemia (T-LGLL) is a lymphoproliferative disease and bone marrow failure syndrome which res …
CD83 expression characterizes precursor exhausted T cell population.
Wu Z, Yoshikawa T, Inoue S, Ito Y, Kasuya H, Nakashima T, Zhang H, Kotaka S, Hosoda W, Suzuki S, Kagoya Y. Wu Z, et al. Among authors: ito y. Commun Biol. 2023 Mar 11;6(1):258. doi: 10.1038/s42003-023-04631-6. Commun Biol. 2023. PMID: 36906640 Free PMC article.
Exhausted T cells include a subpopulation that maintains proliferative capacity, referred to as precursor exhausted T cells (T(PEX)). While functionally distinct and important for antitumor immunity, T(PEX) possess some overlapping phenotypic features …
Exhausted T cells include a subpopulation that maintains proliferative capacity, referred to as precursor exhausted T cells ( …
Induced Pluripotent Stem Cell-Derived T Cells for Cancer Immunotherapy.
Patel SJ, Yamauchi T, Ito F. Patel SJ, et al. Among authors: ito f. Surg Oncol Clin N Am. 2019 Jul;28(3):489-504. doi: 10.1016/j.soc.2019.02.005. Epub 2019 Apr 10. Surg Oncol Clin N Am. 2019. PMID: 31079802 Free PMC article. Review.
Adoptive T cell therapy for solid malignancies is limited because obtaining sufficient numbers of less-differentiated tumor-specific T cells is difficult. This roadblock can be theoretically overcome by the use of induced pluripotent stem cells (iPSCs), which self-r …
Adoptive T cell therapy for solid malignancies is limited because obtaining sufficient numbers of less-differentiated tumor-specific …
SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine.
Mise-Omata S, Ando M, Srirat T, Nakagawara K, Hayakawa T, Iizuka-Koga M, Nishimasu H, Nureki O, Ito M, Yoshimura A. Mise-Omata S, et al. Among authors: ito m. Cell Rep. 2023 Aug 29;42(8):112940. doi: 10.1016/j.celrep.2023.112940. Epub 2023 Aug 14. Cell Rep. 2023. PMID: 37582370 Free article.
Furthermore, Socs3 deficiency reduces regulatory T cells and increases T helper 1 (Th1) cells. SOCS3 knockdown in human chimeric antigen receptor T (CAR-T) cells exhibits a strong anti-tumor response in humanized mice. Thus, genetic disruption of SOCS3 …
Furthermore, Socs3 deficiency reduces regulatory T cells and increases T helper 1 (Th1) cells. SOCS3 knockdown in human chimer …
Cysticercosis/taeniasis in Asia and the Pacific.
Ito A, Wandra T, Yamasaki H, Nakao M, Sako Y, Nakaya K, Margono SS, Suroso T, Gauci C, Lightowlers MW. Ito A, et al. Vector Borne Zoonotic Dis. 2004 Summer;4(2):95-107. doi: 10.1089/1530366041210756. Vector Borne Zoonotic Dis. 2004. PMID: 15228810 Review.
Although there is continuing debate about the definition of a new species, phylogenetic analyses of these parasites have provided multiple lines of evidence that T. asiatica is an independent species and the sister species of T. saginata. Here we review briefly the …
Although there is continuing debate about the definition of a new species, phylogenetic analyses of these parasites have provided multiple l …
28,071 results
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