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Negative DNA supercoiling induces genome-wide Cas9 off-target activity.
Mol Cell. 2023 Oct 5;83(19):3533-3545.e5. doi: 10.1016/j.molcel.2023.09.008.
Mol Cell. 2023.
PMID: 37802026
Free article.
Cas12a target search and cleavage on force-stretched DNA.
Losito M, Smith QM, Newton MD, Cuomo ME, Rueda DS.
Losito M, et al.
Phys Chem Chem Phys. 2021 Dec 8;23(47):26640-26644. doi: 10.1039/d1cp03408a.
Phys Chem Chem Phys. 2021.
PMID: 34494640
Free PMC article.
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