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Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition.
J Med Chem. 2023 Oct 26;66(20):14278-14302. doi: 10.1021/acs.jmedchem.3c01319. Epub 2023 Oct 11.
J Med Chem. 2023.
PMID: 37819647
Free PMC article.
Back-pocket optimization of 2-aminopyrimidine-based macrocycles leads to potent dual EPHA2/GAK kinase inhibitors with antiviral activity.
Gerninghaus J, Zhubi R, Krämer A, Karim M, Tran DHN, Joerger AC, Schreiber C, Berger LM, Berger BT, Ehret TAL, Elson L, Lenz C, Saxena K, Müller S, Einav S, Knapp S, Hanke T.
Gerninghaus J, et al. Among authors: ehret tal.
bioRxiv [Preprint]. 2024 Feb 18:2024.02.18.580805. doi: 10.1101/2024.02.18.580805.
bioRxiv. 2024.
PMID: 38405908
Free PMC article.
Preprint.
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