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2014 1
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Page 1
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.
Simpson DS, Pang J, Weir A, Kong IY, Fritsch M, Rashidi M, Cooney JP, Davidson KC, Speir M, Djajawi TM, Hughes S, Mackiewicz L, Dayton M, Anderton H, Doerflinger M, Deng Y, Huang AS, Conos SA, Tye H, Chow SH, Rahman A, Norton RS, Naderer T, Nicholson SE, Burgio G, Man SM, Groom JR, Herold MJ, Hawkins ED, Lawlor KE, Strasser A, Silke J, Pellegrini M, Kashkar H, Feltham R, Vince JE. Simpson DS, et al. Among authors: speir m. Immunity. 2022 Mar 8;55(3):423-441.e9. doi: 10.1016/j.immuni.2022.01.003. Epub 2022 Feb 8. Immunity. 2022. PMID: 35139355 Free PMC article.
NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils.
Zhu YP, Speir M, Tan Z, Lee JC, Nowell CJ, Chen AA, Amatullah H, Salinger AJ, Huang CJ, Wu G, Peng W, Askari K, Griffis E, Ghassemian M, Santini J, Gerlic M, Kiosses WB, Catz SD, Hoffman HM, Greco KF, Weller E, Thompson PR, Wong LP, Sadreyev R, Jeffrey KL, Croker BA. Zhu YP, et al. Among authors: speir m. Sci Adv. 2023 Dec 22;9(51):eadj1397. doi: 10.1126/sciadv.adj1397. Epub 2023 Dec 20. Sci Adv. 2023. PMID: 38117877 Free PMC article.
Targeting RIP Kinases in Chronic Inflammatory Disease.
Speir M, Djajawi TM, Conos SA, Tye H, Lawlor KE. Speir M, et al. Biomolecules. 2021 Apr 28;11(5):646. doi: 10.3390/biom11050646. Biomolecules. 2021. PMID: 33924766 Free PMC article. Review.
Programmed cell death in Legionella infection.
Speir M, Vince JE, Naderer T. Speir M, et al. Future Microbiol. 2014;9(1):107-18. doi: 10.2217/fmb.13.139. Future Microbiol. 2014. PMID: 24328384 Review.
Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.
Speir M, Nowell CJ, Chen AA, O'Donnell JA, Shamie IS, Lakin PR, D'Cruz AA, Braun RO, Babon JJ, Lewis RS, Bliss-Moreau M, Shlomovitz I, Wang S, Cengia LH, Stoica AI, Hakem R, Kelliher MA, O'Reilly LA, Patsiouras H, Lawlor KE, Weller E, Lewis NE, Roberts AW, Gerlic M, Croker BA. Speir M, et al. Nat Immunol. 2020 Jan;21(1):54-64. doi: 10.1038/s41590-019-0550-7. Epub 2019 Dec 9. Nat Immunol. 2020. PMID: 31819256 Free PMC article.
Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response.
Weerasinghe H, Simm C, Djajawi TM, Tedja I, Lo TL, Simpson DS, Shasha D, Mizrahi N, Olivier FAB, Speir M, Lawlor KE, Ben-Ami R, Traven A. Weerasinghe H, et al. Among authors: speir m. Cell Rep. 2023 May 30;42(5):112522. doi: 10.1016/j.celrep.2023.112522. Epub 2023 May 18. Cell Rep. 2023. PMID: 37204928 Free article.
18 results