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Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition.
Holt AK, Najumudeen AK, Collard TJ, Li H, Millett LM, Hoskin AJ, Legge DN, Mortensson EMH, Flanagan DJ, Jones N, Kollareddy M, Timms P, Hitchings MD, Cronin J, Sansom OJ, Williams AC, Vincent EE. Holt AK, et al. Among authors: legge dn. Cancer Metab. 2023 Oct 19;11(1):18. doi: 10.1186/s40170-023-00318-y. Cancer Metab. 2023. PMID: 37858256 Free PMC article.
Identifying metabolic features of colorectal cancer liability using Mendelian randomization.
Bull CJ, Hazelwood E, Bell JA, Tan VY, Constantinescu AE, Borges MC, Legge DN, Burrows K, Huyghe JR, Brenner H, Castellví-Bel S, Chan AT, Kweon SS, Marchand LL, Li L, Cheng I, Pai RK, Figueiredo JC, Murphy N, Gunter MJ, Timpson NJ, Vincent EE. Bull CJ, et al. Among authors: legge dn. medRxiv [Preprint]. 2023 Nov 9:2023.03.10.23287084. doi: 10.1101/2023.03.10.23287084. medRxiv. 2023. PMID: 36945480 Free PMC article. Updated. Preprint.
Impact of weight loss on cancer-related proteins in serum: results from a cluster randomised controlled trial of individuals with type 2 diabetes.
Bull CJ, Hazelwood E, Legge DN, Corbin LJ, Richardson TG, Lee M, Yarmolinsky J, Smith-Byrne K, Hughes DA, Johansson M, Peters U, Berndt SI, Brenner H, Burnett-Hartman A, Cheng I, Kweon SS, Le Marchand L, Li L, Newcomb PA, Pearlman R, McConnachie A, Welsh P, Taylor R, Lean MEJ, Sattar N, Murphy N, Gunter MJ, Timpson NJ, Vincent EE. Bull CJ, et al. Among authors: legge dn. EBioMedicine. 2024 Feb;100:104977. doi: 10.1016/j.ebiom.2024.104977. Epub 2024 Jan 29. EBioMedicine. 2024. PMID: 38290287 Free PMC article. Clinical Trial.