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Year Number of Results
2010 2
2011 1
2012 1
2013 1
2014 3
2016 1
2018 1
2019 4
2021 1
2022 6
2023 4
2024 5

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Page 1
BacPROTACs mediate targeted protein degradation in bacteria.
Morreale FE, Kleine S, Leodolter J, Junker S, Hoi DM, Ovchinnikov S, Okun A, Kley J, Kurzbauer R, Junk L, Guha S, Podlesainski D, Kazmaier U, Boehmelt G, Weinstabl H, Rumpel K, Schmiedel VM, Hartl M, Haselbach D, Meinhart A, Kaiser M, Clausen T. Morreale FE, et al. Among authors: weinstabl h. Cell. 2022 Jun 23;185(13):2338-2353.e18. doi: 10.1016/j.cell.2022.05.009. Epub 2022 Jun 3. Cell. 2022. PMID: 35662409 Free PMC article.
Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Hoi DM, Junker S, Junk L, Schwechel K, Fischel K, Podlesainski D, Hawkins PME, van Geelen L, Kaschani F, Leodolter J, Morreale FE, Kleine S, Guha S, Rumpel K, Schmiedel VM, Weinstabl H, Meinhart A, Payne RJ, Kaiser M, Hartl M, Boehmelt G, Kazmaier U, Kalscheuer R, Clausen T. Hoi DM, et al. Among authors: weinstabl h. Cell. 2023 May 11;186(10):2176-2192.e22. doi: 10.1016/j.cell.2023.04.009. Epub 2023 May 2. Cell. 2023. PMID: 37137307 Free article.
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.
Farnaby W, Koegl M, Roy MJ, Whitworth C, Diers E, Trainor N, Zollman D, Steurer S, Karolyi-Oezguer J, Riedmueller C, Gmaschitz T, Wachter J, Dank C, Galant M, Sharps B, Rumpel K, Traxler E, Gerstberger T, Schnitzer R, Petermann O, Greb P, Weinstabl H, Bader G, Zoephel A, Weiss-Puxbaum A, Ehrenhöfer-Wölfer K, Wöhrle S, Boehmelt G, Rinnenthal J, Arnhof H, Wiechens N, Wu MY, Owen-Hughes T, Ettmayer P, Pearson M, McConnell DB, Ciulli A. Farnaby W, et al. Among authors: weinstabl h. Nat Chem Biol. 2019 Jul;15(7):672-680. doi: 10.1038/s41589-019-0294-6. Epub 2019 Jun 10. Nat Chem Biol. 2019. PMID: 31178587 Free PMC article.
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo.
Kofink C, Trainor N, Mair B, Wöhrle S, Wurm M, Mischerikow N, Roy MJ, Bader G, Greb P, Garavel G, Diers E, McLennan R, Whitworth C, Vetma V, Rumpel K, Scharnweber M, Fuchs JE, Gerstberger T, Cui Y, Gremel G, Chetta P, Hopf S, Budano N, Rinnenthal J, Gmaschitz G, Mayer M, Koegl M, Ciulli A, Weinstabl H, Farnaby W. Kofink C, et al. Among authors: weinstabl h. Nat Commun. 2022 Oct 10;13(1):5969. doi: 10.1038/s41467-022-33430-6. Nat Commun. 2022. PMID: 36216795 Free PMC article.
Electrochemical Umpolung C-H Functionalization of Oxindoles.
Pastor M, Vayer M, Weinstabl H, Maulide N. Pastor M, et al. Among authors: weinstabl h. J Org Chem. 2022 Jan 7;87(1):606-612. doi: 10.1021/acs.joc.1c02616. Epub 2021 Dec 28. J Org Chem. 2022. PMID: 34962127 Free PMC article.
European Medicinal Chemistry Leaders in Industry (EMCL) - On the Status and Future of Medicinal Chemistry Research in Europe.
Ali A, Bauser M, Bertrand S, Blackaby W, Boss C, Bossart M, Hall A, Binch H, Czechtizky W, Gijsen H, Haning H, Hartung IV, Kilburn P, Lassalle G, Lücking U, Mack J, Missbach M, Otsomaa L, Torrens A, Wagner M, Walter M, Weinstabl H, van Hijfte L, von Nussbaum F. Ali A, et al. Among authors: weinstabl h. ChemMedChem. 2023 Jul 3;18(13):e202300127. doi: 10.1002/cmdc.202300127. Epub 2023 Jun 5. ChemMedChem. 2023. PMID: 37276375 Review.
opnMe.com: a digital initiative for sharing tools with the biomedical research community.
Gollner A, Köster M, Nicklin P, Trieselmann T, Klein E, Vlach J, Heine C, Grundl M, Ramharter J, Wyatt D, Chaturvedi M, Ciulli A, Carter KC, Müller S, Bischoff D, Ettmayer P, Haaksma E, Mack J, McConnell D, Stenkamp D, Weinstabl H, Zentgraf M, Wood CR, Montel F. Gollner A, et al. Among authors: weinstabl h. Nat Rev Drug Discov. 2022 Jul;21(7):475-476. doi: 10.1038/d41573-022-00071-9. Nat Rev Drug Discov. 2022. PMID: 35459938 No abstract available.
Inhibition of p53-MDM2 binding reduces senescent cell abundance and improves the adaptive responses of skeletal muscle from aged mice.
Nolt GL, Keeble AR, Wen Y, Strong AC, Thomas NT, Valentino TR, Brightwell CR, Murach KA, Patrizia S, Weinstabl H, Gollner A, McCarthy JJ, Fry CS, Franti M, Filareto A, Peterson CA, Dungan CM. Nolt GL, et al. Among authors: weinstabl h. Geroscience. 2024 Apr;46(2):2153-2176. doi: 10.1007/s11357-023-00976-2. Epub 2023 Oct 24. Geroscience. 2024. PMID: 37872294 Free PMC article.
Synthesis of the lycopodium alkaloid (+)-lycoflexine.
Ramharter J, Weinstabl H, Mulzer J. Ramharter J, et al. Among authors: weinstabl h. J Am Chem Soc. 2010 Oct 20;132(41):14338-9. doi: 10.1021/ja107533m. J Am Chem Soc. 2010. PMID: 20866095
25 results