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2020 2
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N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity.
Varland S, Silva RD, Kjosås I, Faustino A, Bogaert A, Billmann M, Boukhatmi H, Kellen B, Costanzo M, Drazic A, Osberg C, Chan K, Zhang X, Tong AHY, Andreazza S, Lee JJ, Nedyalkova L, Ušaj M, Whitworth AJ, Andrews BJ, Moffat J, Myers CL, Gevaert K, Boone C, Martinho RG, Arnesen T. Varland S, et al. Among authors: bogaert a. Nat Commun. 2023 Oct 27;14(1):6774. doi: 10.1038/s41467-023-42342-y. Nat Commun. 2023. PMID: 37891180 Free PMC article.
N-Terminal Proteoforms in Human Disease.
Bogaert A, Fernandez E, Gevaert K. Bogaert A, et al. Trends Biochem Sci. 2020 Apr;45(4):308-320. doi: 10.1016/j.tibs.2019.12.009. Epub 2020 Jan 27. Trends Biochem Sci. 2020. PMID: 32001092 Free article. Review.
Protein amino-termini and how to identify them.
Bogaert A, Gevaert K. Bogaert A, et al. Expert Rev Proteomics. 2020 Jul-Aug;17(7-8):581-594. doi: 10.1080/14789450.2020.1821657. Epub 2020 Sep 20. Expert Rev Proteomics. 2020. PMID: 32896182 Review.
N-terminal proteoforms may engage in different protein complexes.
Bogaert A, Fijalkowska D, Staes A, Van de Steene T, Vuylsteke M, Stadler C, Eyckerman S, Spirohn K, Hao T, Calderwood MA, Gevaert K. Bogaert A, et al. Life Sci Alliance. 2023 Jun 14;6(8):e202301972. doi: 10.26508/lsa.202301972. Print 2023 Aug. Life Sci Alliance. 2023. PMID: 37316325 Free PMC article.