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Dapagliflozin Prevents Kidney Glycogen Accumulation and Improves Renal Proximal Tubule Cell Functions in a Mouse Model of Glycogen Storage Disease Type 1b.
J Am Soc Nephrol. 2022 Oct;33(10):1864-1875. doi: 10.1681/ASN.2021070935. Epub 2022 Jul 12.
J Am Soc Nephrol. 2022.
PMID: 35820785
Free PMC article.
The SGLT2 inhibitor dapagliflozin improves kidney function in glycogen storage disease XI.
Trepiccione F, Iervolino A, D'Acierno M, Siccardi S, Costanzo V, Sardella D, De La Motte LR, D'Apolito L, Miele A, Perna AF, Capolongo G, Zacchia M, Frische S, Nielsen R, Staiano L, Sambri I, De Cegli R, Unwin R, Eladari D, Capasso G.
Trepiccione F, et al. Among authors: siccardi s.
Sci Transl Med. 2023 Nov;15(720):eabn4214. doi: 10.1126/scitranslmed.abn4214. Epub 2023 Nov 1.
Sci Transl Med. 2023.
PMID: 37910600
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Potassium depletion induces cellular conversion in the outer medullary collecting duct altering Notch signaling pathway.
Iervolino A, Prosperi F, De La Motte LR, Petrillo F, Spagnuolo M, D'Acierno M, Siccardi S, Perna AF, Christensen BM, Frische S, Capasso G, Trepiccione F.
Iervolino A, et al. Among authors: siccardi s.
Sci Rep. 2020 Mar 31;10(1):5708. doi: 10.1038/s41598-020-61882-7.
Sci Rep. 2020.
PMID: 32235870
Free PMC article.
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