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Year Number of Results
2003 1
2004 1
2005 2
2008 1
2009 1
2010 2
2011 2
2012 1
2013 4
2015 1
2023 1
2024 1

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17 results

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Page 1
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.
Varkaris A, Pazolli E, Gunaydin H, Wang Q, Pierce L, Boezio AA, Bulku A, DiPietro L, Fridrich C, Frost A, Giordanetto F, Hamilton EP, Harris K, Holliday M, Hunter TL, Iskandar A, Ji Y, Larivée A, LaRochelle JR, Lescarbeau A, Llambi F, Lormil B, Mader MM, Mar BG, Martin I, McLean TH, Michelsen K, Pechersky Y, Puente-Poushnejad E, Raynor K, Rogala D, Samadani R, Schram AM, Shortsleeves K, Swaminathan S, Tajmir S, Tan G, Tang Y, Valverde R, Wehrenberg B, Wilbur J, Williams BR, Zeng H, Zhang H, Walters WP, Wolf BB, Shaw DE, Bergstrom DA, Watters J, Fraser JS, Fortin PD, Kipp DR. Varkaris A, et al. Among authors: wilbur j. Cancer Discov. 2024 Feb 8;14(2):240-257. doi: 10.1158/2159-8290.CD-23-0944. Cancer Discov. 2024. PMID: 37916956 Free PMC article.
Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors.
Taylor AM, Williams BR, Giordanetto F, Kelley EH, Lescarbeau A, Shortsleeves K, Tang Y, Walters WP, Arrazate A, Bowman C, Brophy E, Chan EW, Deshmukh G, Greisman JB, Hunsaker TL, Kipp DR, Saenz Lopez-Larrocha P, Maddalo D, Martin IJ, Maragakis P, Merchant M, Murcko M, Nisonoff H, Nguyen V, Nguyen V, Orozco O, Owen C, Pierce L, Schmidt M, Shaw DE, Smith S, Therrien E, Tran JC, Watters J, Waters NJ, Wilbur J, Willmore L. Taylor AM, et al. Among authors: wilbur j. J Med Chem. 2023 Oct 12;66(19):13384-13399. doi: 10.1021/acs.jmedchem.3c00483. Epub 2023 Sep 29. J Med Chem. 2023. PMID: 37774359
Interplay between spindle architecture and function.
Helmke KJ, Heald R, Wilbur JD. Helmke KJ, et al. Among authors: wilbur jd. Int Rev Cell Mol Biol. 2013;306:83-125. doi: 10.1016/B978-0-12-407694-5.00003-1. Int Rev Cell Mol Biol. 2013. PMID: 24016524 Review.
New faces of the familiar clathrin lattice.
Wilbur JD, Hwang PK, Brodsky FM. Wilbur JD, et al. Traffic. 2005 Apr;6(4):346-50. doi: 10.1111/j.1600-0854.2005.00277.x. Traffic. 2005. PMID: 15752139 Free article. Review.
A comparative analysis of spindle morphometrics across metazoans.
Crowder ME, Strzelecka M, Wilbur JD, Good MC, von Dassow G, Heald R. Crowder ME, et al. Among authors: wilbur jd. Curr Biol. 2015 Jun 1;25(11):1542-50. doi: 10.1016/j.cub.2015.04.036. Epub 2015 May 21. Curr Biol. 2015. PMID: 26004761 Free PMC article.
17 results