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Year Number of Results
2008 1
2010 1
2012 3
2013 2
2014 1
2016 1
2018 1
2020 1
2021 1
2022 1
2023 2
2024 1

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15 results

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Page 1
Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism.
Pham VN, Bruemmer KJ, Toh JDW, Ge EJ, Tenney L, Ward CC, Dingler FA, Millington CL, Garcia-Prieto CA, Pulos-Holmes MC, Ingolia NT, Pontel LB, Esteller M, Patel KJ, Nomura DK, Chang CJ. Pham VN, et al. Among authors: millington cl. Science. 2023 Nov 3;382(6670):eabp9201. doi: 10.1126/science.abp9201. Epub 2023 Nov 3. Science. 2023. PMID: 37917677
Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response.
Mulderrig L, Garaycoechea JI, Tuong ZK, Millington CL, Dingler FA, Ferdinand JR, Gaul L, Tadross JA, Arends MJ, O'Rahilly S, Crossan GP, Clatworthy MR, Patel KJ. Mulderrig L, et al. Among authors: millington cl. Nature. 2021 Dec;600(7887):158-163. doi: 10.1038/s41586-021-04133-7. Epub 2021 Nov 24. Nature. 2021. PMID: 34819667
Efficient Synthesis of DNA Duplexes Containing Reduced Acetaldehyde Interstrand Cross-Links.
Morton SB, Finger LD, van der Sluijs R, Mulcrone WD, Hodskinson M, Millington CL, Vanhinsbergh C, Patel KJ, Dickman MJ, Knipscheer P, Grasby JA, Williams DM. Morton SB, et al. Among authors: millington cl. J Am Chem Soc. 2023 Jan 18;145(2):953-959. doi: 10.1021/jacs.2c10070. Epub 2022 Dec 30. J Am Chem Soc. 2023. PMID: 36584283 Free PMC article.
Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.
Dingler FA, Wang M, Mu A, Millington CL, Oberbeck N, Watcham S, Pontel LB, Kamimae-Lanning AN, Langevin F, Nadler C, Cordell RL, Monks PS, Yu R, Wilson NK, Hira A, Yoshida K, Mori M, Okamoto Y, Okuno Y, Muramatsu H, Shiraishi Y, Kobayashi M, Moriguchi T, Osumi T, Kato M, Miyano S, Ito E, Kojima S, Yabe H, Yabe M, Matsuo K, Ogawa S, Göttgens B, Hodskinson MRG, Takata M, Patel KJ. Dingler FA, et al. Among authors: millington cl. Mol Cell. 2020 Dec 17;80(6):996-1012.e9. doi: 10.1016/j.molcel.2020.10.012. Epub 2020 Nov 3. Mol Cell. 2020. PMID: 33147438 Free PMC article.
Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines.
Latypov VF, Tubbs JL, Watson AJ, Marriott AS, McGown G, Thorncroft M, Wilkinson OJ, Senthong P, Butt A, Arvai AS, Millington CL, Povey AC, Williams DM, Santibanez-Koref MF, Tainer JA, Margison GP. Latypov VF, et al. Among authors: millington cl. Mol Cell. 2012 Jul 13;47(1):50-60. doi: 10.1016/j.molcel.2012.04.028. Epub 2012 May 31. Mol Cell. 2012. PMID: 22658721 Free PMC article.
Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-π interactions.
Wilkinson OJ, Latypov V, Tubbs JL, Millington CL, Morita R, Blackburn H, Marriott A, McGown G, Thorncroft M, Watson AJ, Connolly BA, Grasby JA, Masui R, Hunter CA, Tainer JA, Margison GP, Williams DM. Wilkinson OJ, et al. Among authors: millington cl. Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18755-60. doi: 10.1073/pnas.1209451109. Epub 2012 Oct 29. Proc Natl Acad Sci U S A. 2012. PMID: 23112169 Free PMC article.
The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase.
Senthong P, Millington CL, Wilkinson OJ, Marriott AS, Watson AJ, Reamtong O, Eyers CE, Williams DM, Margison GP, Povey AC. Senthong P, et al. Among authors: millington cl. Nucleic Acids Res. 2013 Mar 1;41(5):3047-55. doi: 10.1093/nar/gks1476. Epub 2013 Jan 17. Nucleic Acids Res. 2013. PMID: 23335782 Free PMC article.
15 results