Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 1
2006 1
2007 1
2009 1
2010 1
2011 1
2012 3
2013 1
2014 2
2015 4
2016 1
2017 2
2018 1
2020 1
2021 3
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

23 results

Results by year

Filters applied: . Clear all
Page 1
Senescent cells: an emerging target for diseases of ageing.
Childs BG, Gluscevic M, Baker DJ, Laberge RM, Marquess D, Dananberg J, van Deursen JM. Childs BG, et al. Among authors: laberge rm. Nat Rev Drug Discov. 2017 Oct;16(10):718-735. doi: 10.1038/nrd.2017.116. Epub 2017 Jul 21. Nat Rev Drug Discov. 2017. PMID: 28729727 Free PMC article. Review.
An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Demaria M, Ohtani N, Youssef SA, Rodier F, Toussaint W, Mitchell JR, Laberge RM, Vijg J, Van Steeg H, Dollé ME, Hoeijmakers JH, de Bruin A, Hara E, Campisi J. Demaria M, et al. Among authors: laberge rm. Dev Cell. 2014 Dec 22;31(6):722-33. doi: 10.1016/j.devcel.2014.11.012. Epub 2014 Dec 11. Dev Cell. 2014. PMID: 25499914 Free PMC article.
p21 produces a bioactive secretome that places stressed cells under immunosurveillance.
Sturmlechner I, Zhang C, Sine CC, van Deursen EJ, Jeganathan KB, Hamada N, Grasic J, Friedman D, Stutchman JT, Can I, Hamada M, Lim DY, Lee JH, Ordog T, Laberge RM, Shapiro V, Baker DJ, Li H, van Deursen JM. Sturmlechner I, et al. Among authors: laberge rm. Science. 2021 Oct 29;374(6567):eabb3420. doi: 10.1126/science.abb3420. Epub 2021 Oct 29. Science. 2021. PMID: 34709885 Free PMC article.
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.
Chang J, Wang Y, Shao L, Laberge RM, Demaria M, Campisi J, Janakiraman K, Sharpless NE, Ding S, Feng W, Luo Y, Wang X, Aykin-Burns N, Krager K, Ponnappan U, Hauer-Jensen M, Meng A, Zhou D. Chang J, et al. Among authors: laberge rm. Nat Med. 2016 Jan;22(1):78-83. doi: 10.1038/nm.4010. Epub 2015 Dec 14. Nat Med. 2016. PMID: 26657143 Free PMC article.
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
Laberge RM, Sun Y, Orjalo AV, Patil CK, Freund A, Zhou L, Curran SC, Davalos AR, Wilson-Edell KA, Liu S, Limbad C, Demaria M, Li P, Hubbard GB, Ikeno Y, Javors M, Desprez PY, Benz CC, Kapahi P, Nelson PS, Campisi J. Laberge RM, et al. Nat Cell Biol. 2015 Aug;17(8):1049-61. doi: 10.1038/ncb3195. Epub 2015 Jul 6. Nat Cell Biol. 2015. PMID: 26147250 Free PMC article.
p53: Pro-aging or pro-longevity?
de Keizer PL, Laberge RM, Campisi J. de Keizer PL, et al. Among authors: laberge rm. Aging (Albany NY). 2010 Jul;2(7):377-9. doi: 10.18632/aging.100178. Aging (Albany NY). 2010. PMID: 20657035 Free PMC article. No abstract available.
Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence.
Savić R, Yang J, Koplev S, An MC, Patel PL, O'Brien RN, Dubose BN, Dodatko T, Rogatsky E, Sukhavasi K, Ermel R, Ruusalepp A, Houten SM, Kovacic JC, Stewart AF, Yohn CB, Schadt EE, Laberge RM, Björkegren JLM, Tu Z, Argmann C. Savić R, et al. Among authors: laberge rm. Cell Rep. 2023 Nov 28;42(11):113371. doi: 10.1016/j.celrep.2023.113371. Epub 2023 Nov 7. Cell Rep. 2023. PMID: 37938972 Free PMC article.
23 results