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PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma.
Frenster JD, Erdjument-Bromage H, Stephan G, Ravn-Boess N, Wang S, Liu W, Bready D, Wilcox J, Kieslich B, Jankovic M, Wilde C, Horn S, Sträter N, Liebscher I, Schöneberg T, Fenyo D, Neubert TA, Placantonakis DG. Frenster JD, et al. Cell Rep. 2023 Jul 25;42(7):112679. doi: 10.1016/j.celrep.2023.112679. Epub 2023 Jun 23. Cell Rep. 2023. PMID: 37354459 Free PMC article.
The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability.
Ravn-Boess N, Roy N, Hattori T, Bready D, Donaldson H, Lawson C, Lapierre C, Korman A, Rodrick T, Liu E, Frenster JD, Stephan G, Wilcox J, Corrado AD, Cai J, Ronnen R, Wang S, Haddock S, Sabio Ortiz J, Mishkit O, Khodadadi-Jamayran A, Tsirigos A, Fenyö D, Zagzag D, Drube J, Hoffmann C, Perna F, Jones DR, Possemato R, Koide A, Koide S, Park CY, Placantonakis DG. Ravn-Boess N, et al. Among authors: frenster jd. Cell Rep. 2023 Nov 28;42(11):113374. doi: 10.1016/j.celrep.2023.113374. Epub 2023 Nov 8. Cell Rep. 2023. PMID: 37938973 Free PMC article.
The H3K36me2 writer-reader dependency in H3K27M-DIPG.
Yu JR, LeRoy G, Bready D, Frenster JD, Saldaña-Meyer R, Jin Y, Descostes N, Stafford JM, Placantonakis DG, Reinberg D. Yu JR, et al. Among authors: frenster jd. Sci Adv. 2021 Jul 14;7(29):eabg7444. doi: 10.1126/sciadv.abg7444. Print 2021 Jul. Sci Adv. 2021. PMID: 34261657 Free PMC article.
GPR133 Promotes Glioblastoma Growth in Hypoxia.
Frenster JD, Inocencio JF, Xu Z, Dhaliwal J, Alghamdi A, Zagzag D, Bayin NS, Placantonakis DG. Frenster JD, et al. Neurosurgery. 2017 Sep 1;64(CN_suppl_1):177-181. doi: 10.1093/neuros/nyx227. Neurosurgery. 2017. PMID: 28899043 Free PMC article. No abstract available.
Isolation of Glioblastoma Stem Cells with Flow Cytometry.
Inocencio J, Frenster JD, Placantonakis DG. Inocencio J, et al. Among authors: frenster jd. Methods Mol Biol. 2018;1741:71-79. doi: 10.1007/978-1-4939-7659-1_5. Methods Mol Biol. 2018. PMID: 29392691
Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells.
Bayin NS, Frenster JD, Sen R, Si S, Modrek AS, Galifianakis N, Dolgalev I, Ortenzi V, Illa-Bochaca I, Khahera A, Serrano J, Chiriboga L, Zagzag D, Golfinos JG, Doyle W, Tsirigos A, Heguy A, Chesler M, Barcellos-Hoff MH, Snuderl M, Placantonakis DG. Bayin NS, et al. Among authors: frenster jd. Oncotarget. 2017 May 23;8(39):64932-64953. doi: 10.18632/oncotarget.18117. eCollection 2017 Sep 12. Oncotarget. 2017. PMID: 29029402 Free PMC article.
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